Cancertope: In silico Platform for designing genome-based Personalized immunotherapy or Vaccine against Cancer

Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE

Protein	Neoepitopes	Tissue	Position	Prot Mutation	cDNA Mutation	Mutation Type	Num Mismatch	Promiscuity (%)	Cell Line	CTL	MHC I	NHLApred	MHC II	Bcell
Result		Search:
TNFAIP3	AAPLEAPCL	LARGE_INTESTINE	662	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	11	0	0	N
TNFAIP3	AHCVSSSTE	LARGE_INTESTINE	624	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	ALFCSVRPL	ENDOMETRIUM	466	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	Y	16	9	0	N
TNFAIP3	APCLKDTAR	LARGE_INTESTINE	667	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	Y	3	9	0	N
TNFAIP3	APLEAPCLK	LARGE_INTESTINE	663	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	3	0	0	N
TNFAIP3	ARSVSLKLR	LARGE_INTESTINE	674	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	3	0	0	N
TNFAIP3	AWGGNAAPL	LARGE_INTESTINE	657	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	6	0	0	N
TNFAIP3	CLKDTARSV	LARGE_INTESTINE	669	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	4	9	0	N
TNFAIP3	CVSSSTEKT	LARGE_INTESTINE	626	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	N
TNFAIP3	DFMRPKGQK	LARGE_INTESTINE	685	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	N
TNFAIP3	DTARSVSLK	LARGE_INTESTINE	672	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	3	11	0	N
TNFAIP3	EAPCLKDTA	LARGE_INTESTINE	666	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	2	0	0	N
TNFAIP3	EESTGGLIR	ENDOMETRIUM	451	p.G455fs	c.1363_1363delG	Frame_Shift_Del	3	0.11	MFE319	N	0	0	0	N
TNFAIP3	EKTNILLLP	LARGE_INTESTINE	632	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	ENKGFAHCV	LARGE_INTESTINE	619	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	1	0	0	N
TNFAIP3	ESTGGLIRP	ENDOMETRIUM	452	p.G455fs	c.1363_1363delG	Frame_Shift_Del	4	0.11	MFE319	N	0	0	0	N
TNFAIP3	FAHCVSSST	LARGE_INTESTINE	623	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	6	0	0	N
TNFAIP3	FMRPKGQKS	LARGE_INTESTINE	686	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	2	0	0	N
TNFAIP3	FRAWGGNAA	LARGE_INTESTINE	655	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	Y	5	10	9	N
TNFAIP3	GFAHCVSSS	LARGE_INTESTINE	622	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	N
TNFAIP3	GGLIRPHRQ	ENDOMETRIUM	455	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	0	0	0	N
TNFAIP3	GGNAAPLEA	LARGE_INTESTINE	659	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	0	0	0	N
TNFAIP3	GKSVPQRPG	LARGE_INTESTINE	642	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	GLIRPHRQH	ENDOMETRIUM	456	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	0	0	0	N
TNFAIP3	GNAAPLEAP	LARGE_INTESTINE	660	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	GSRTPFRAW	LARGE_INTESTINE	650	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	Y	3	9	0	N
TNFAIP3	GTPENKGFA	LARGE_INTESTINE	616	p.F623fs	c.1867_1867delT	Frame_Shift_Del	1	0.11	LOVO	N	3	0	0	N
TNFAIP3	HCVSSSTEK	LARGE_INTESTINE	625	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	2	0	0	N
TNFAIP3	HPALFCSVR	ENDOMETRIUM	464	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	Y	4	9	0	N
TNFAIP3	HRQHPALFC	ENDOMETRIUM	461	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	2	0	0	N
TNFAIP3	ILLLPQGKS	LARGE_INTESTINE	636	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	11	N
TNFAIP3	IRDFMRPKG	LARGE_INTESTINE	683	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	1	0	5	Y
TNFAIP3	IRPHRQHPA	ENDOMETRIUM	458	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	6	0	18	Y
TNFAIP3	KDTARSVSL	LARGE_INTESTINE	671	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	6	0	0	N
TNFAIP3	KGFAHCVSS	LARGE_INTESTINE	621	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	1	0	0	N
TNFAIP3	KLRIRDFMR	LARGE_INTESTINE	680	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	8	10	0	Y
TNFAIP3	KSVPQRPGS	LARGE_INTESTINE	643	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	1	0	0	N
TNFAIP3	KTNILLLPQ	LARGE_INTESTINE	633	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	2	0	0	N
TNFAIP3	LEAPCLKDT	LARGE_INTESTINE	665	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	5	0	0	N
TNFAIP3	LFCSVRPLP	ENDOMETRIUM	467	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	0	0	0	N
TNFAIP3	LIRPHRQHP	ENDOMETRIUM	457	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	0	0	0	N
TNFAIP3	LKDTARSVS	LARGE_INTESTINE	670	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	1	0	0	N
TNFAIP3	LKLRIRDFM	LARGE_INTESTINE	679	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	7	0	8	Y
TNFAIP3	LLLPQGKSV	LARGE_INTESTINE	637	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	7	0	0	N
TNFAIP3	LLPQGKSVP	LARGE_INTESTINE	638	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	LPQGKSVPQ	LARGE_INTESTINE	639	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	2	0	0	Y
TNFAIP3	LRIRDFMRP	LARGE_INTESTINE	681	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	1	0	9	N
TNFAIP3	MRPKGQKSN	LARGE_INTESTINE	687	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	2	0	6	N
TNFAIP3	NAAPLEAPC	LARGE_INTESTINE	661	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	2	0	0	N
TNFAIP3	NILLLPQGK	LARGE_INTESTINE	635	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	4	0	0	N
TNFAIP3	NKGFAHCVS	LARGE_INTESTINE	620	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	1	0	0	N
TNFAIP3	NPEESTGGL	ENDOMETRIUM	449	p.G455fs	c.1363_1363delG	Frame_Shift_Del	1	0.11	MFE319	N	15	0	0	N
TNFAIP3	PALFCSVRP	ENDOMETRIUM	465	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	0	0	0	N
TNFAIP3	PCLKDTARS	LARGE_INTESTINE	668	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	PEESTGGLI	ENDOMETRIUM	450	p.G455fs	c.1363_1363delG	Frame_Shift_Del	2	0.11	MFE319	N	2	0	0	Y
TNFAIP3	PENKGFAHC	LARGE_INTESTINE	618	p.F623fs	c.1867_1867delT	Frame_Shift_Del	3	0.11	LOVO	N	0	0	0	N
TNFAIP3	PFRAWGGNA	LARGE_INTESTINE	654	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	PGSRTPFRA	LARGE_INTESTINE	649	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	PHRQHPALF	ENDOMETRIUM	460	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	0	0	0	N
TNFAIP3	PLEAPCLKD	LARGE_INTESTINE	664	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	N
TNFAIP3	PQGKSVPQR	LARGE_INTESTINE	640	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	1	0	0	N
TNFAIP3	PQRPGSRTP	LARGE_INTESTINE	646	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	Y
TNFAIP3	QGKSVPQRP	LARGE_INTESTINE	641	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	QHPALFCSV	ENDOMETRIUM	463	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	4	0	0	N
TNFAIP3	QRPGSRTPF	LARGE_INTESTINE	647	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	5	0	0	N
TNFAIP3	RAWGGNAAP	LARGE_INTESTINE	656	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	RDFMRPKGQ	LARGE_INTESTINE	684	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	Y
TNFAIP3	RIRDFMRPK	LARGE_INTESTINE	682	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	Y	2	10	0	Y
TNFAIP3	RPGSRTPFR	LARGE_INTESTINE	648	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	4	0	0	N
TNFAIP3	RPHRQHPAL	ENDOMETRIUM	459	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	Y	17	11	0	Y
TNFAIP3	RQHPALFCS	ENDOMETRIUM	462	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	2	0	0	N
TNFAIP3	RSVSLKLRI	LARGE_INTESTINE	675	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	8	0	0	N
TNFAIP3	RTPFRAWGG	LARGE_INTESTINE	652	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	SLKLRIRDF	LARGE_INTESTINE	678	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	4	9	0	N
TNFAIP3	SRTPFRAWG	LARGE_INTESTINE	651	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	1	9	0	N
TNFAIP3	SSSTEKTNI	LARGE_INTESTINE	628	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	4	0	0	N
TNFAIP3	SSTEKTNIL	LARGE_INTESTINE	629	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	10	0	0	N
TNFAIP3	STEKTNILL	LARGE_INTESTINE	630	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	Y	7	11	0	N
TNFAIP3	STGGLIRPH	ENDOMETRIUM	453	p.G455fs	c.1363_1363delG	Frame_Shift_Del	5	0.11	MFE319	N	0	0	0	N
TNFAIP3	SVPQRPGSR	LARGE_INTESTINE	644	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	5	10	0	N
TNFAIP3	SVSLKLRIR	LARGE_INTESTINE	676	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	Y	4	9	0	N
TNFAIP3	TARSVSLKL	LARGE_INTESTINE	673	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	10	0	0	N
TNFAIP3	TEKTNILLL	LARGE_INTESTINE	631	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	Y	9	10	0	N
TNFAIP3	TGGLIRPHR	ENDOMETRIUM	454	p.G455fs	c.1363_1363delG	Frame_Shift_Del	6	0.11	MFE319	N	1	0	0	N
TNFAIP3	TNILLLPQG	LARGE_INTESTINE	634	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	0	N
TNFAIP3	TPENKGFAH	LARGE_INTESTINE	617	p.F623fs	c.1867_1867delT	Frame_Shift_Del	2	0.11	LOVO	N	1	0	0	N
TNFAIP3	TPFRAWGGN	LARGE_INTESTINE	653	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	5	0	0	N
TNFAIP3	VPQRPGSRT	LARGE_INTESTINE	645	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	5	0	0	N
TNFAIP3	VSLKLRIRD	LARGE_INTESTINE	677	p.F623fs	c.1867_1867delT	Frame_Shift_Del	5	0.11	LOVO	N	0	0	4	N
TNFAIP3	VSSSTEKTN	LARGE_INTESTINE	627	p.F623fs	c.1867_1867delT	Frame_Shift_Del	6	0.11	LOVO	N	0	0	0	N
TNFAIP3	WGGNAAPLE	LARGE_INTESTINE	658	p.F623fs	c.1867_1867delT	Frame_Shift_Del	4	0.11	LOVO	N	2	0	0	N
TNFAIP3	ALCGAENER	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	94	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	5	0.11	SUPHD1	N	5	0	0	N
TNFAIP3	EVRKLVALC	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	88	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	1	0.11	SUPHD1	N	2	0	0	N
TNFAIP3	KLVALCGAE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	91	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	4	0.11	SUPHD1	N	0	0	0	N
TNFAIP3	LVALCGAEN	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	92	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	5	0.11	SUPHD1	N	0	0	3	Y
TNFAIP3	RKLVALCGA	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	90	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	3	0.11	SUPHD1	N	3	0	0	N
TNFAIP3	VALCGAENE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	93	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	5	0.11	SUPHD1	N	0	0	0	N
TNFAIP3	VRKLVALCG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	89	p.L92fs	c.274_275insTTGTGGCGCT	Frame_Shift_Ins	2	0.11	SUPHD1	N	1	0	35	N
TNFAIP3	AAEASSSLS	LUNG	544	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	2	0	0	N
TNFAIP3	AKRTKEQLR	LUNG	689	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
TNFAIP3	ALFSTIKET	LARGE_INTESTINE	125	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	4	0	0	N
TNFAIP3	APEDPPKQH	LUNG	753	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	0	0	0	N
TNFAIP3	APPTTPSPF	LARGE_INTESTINE	460	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	14	0	0	N
TNFAIP3	ASASGKVSP	LUNG	638	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	0	0	0	N
TNFAIP3	ASRFQNTIL	LUNG	648	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	6	0	0	N
TNFAIP3	ATSQHMWGV	ENDOMETRIUM	107	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	Y	3	13	0	N
TNFAIP3	AVPLVNRDW	OESOPHAGUS	272	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	1	0	0	N
TNFAIP3	CFKFKQMYG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	782	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	0	0	0	N
TNFAIP3	CFKRTAAEA	LUNG	539	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	1	0	0	N
TNFAIP3	CFTEAQNQR	LUNG	677	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	2	0	0	N
TNFAIP3	CHQCSERRQ	URINARY_TRACT	404	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	0	0	0	N
TNFAIP3	CHQHSKSDP	LARGE_INTESTINE	559	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
TNFAIP3	CLMHATSQH	ENDOMETRIUM	103	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	CNECFKFKQ	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	779	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	1	0	0	N
TNFAIP3	CNFKFRWQL	LUNG	136	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	Y	14	14	0	N
TNFAIP3	CPFFLSVNT	LUNG	392	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	6	0	0	N
TNFAIP3	CQKCFTEAQ	LUNG	674	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	1	0	0	N
TNFAIP3	CREVRKLVV	STOMACH	86	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	4	0	0	N
TNFAIP3	CSTCFKRTA	LUNG	536	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	1	0	0	N
TNFAIP3	DHENEMKEK	LARGE_INTESTINE	293	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	1	0	0	N
TNFAIP3	DHGTTYLIN	LUNG	318	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	1	0	0	N
TNFAIP3	DIFEPTNGI	ENDOMETRIUM	28	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	7	0	0	N
TNFAIP3	DPPKQHCRA	LUNG	756	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	9	0	0	N
TNFAIP3	DPSPLVRSP	LUNG	566	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	0	0	0	N
TNFAIP3	DTCNFKFRW	LUNG	134	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	Y	1	10	0	N
TNFAIP3	DWGRFEDLK	OESOPHAGUS	279	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	0	0	0	N
TNFAIP3	EAKRTKEQL	LUNG	688	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	Y	8	11	0	N
TNFAIP3	ECFKFKQMY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	781	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	5	0	0	N
TNFAIP3	EDIFEPTNG	ENDOMETRIUM	27	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
TNFAIP3	EDPPKQHCR	LUNG	755	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	0	0	0	N
TNFAIP3	EELPGMALG	SKIN	428	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	Y	2	9	0	N
TNFAIP3	EGYCQKCFT	LUNG	671	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	4	0	0	N
TNFAIP3	ELPGMALGA	SKIN	429	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	2	0	0	N
TNFAIP3	ENKHFASAS	LUNG	633	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	0	0	0	N
TNFAIP3	EPTNGIIHH	ENDOMETRIUM	31	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
TNFAIP3	ERTPEDIFE	ENDOMETRIUM	23	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	0	0	0	Y
TNFAIP3	ESQKKLSWC	ENDOMETRIUM	78	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	2	0	0	N
TNFAIP3	ETDTCNFKF	LUNG	132	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	4	0	0	N
TNFAIP3	ETPNCPFFL	LUNG	388	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	8	0	0	N
TNFAIP3	ETTTMKCRS	LARGE_INTESTINE	472	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
TNFAIP3	EVRKLVVLK	STOMACH	88	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	Y	4	17	0	N
TNFAIP3	FASASGKVS	LUNG	637	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	3	0	0	N
TNFAIP3	FEPTNGIIH	ENDOMETRIUM	30	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	3	0	2	N
TNFAIP3	FFLSVNTQP	LUNG	394	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	2	0	4	N
TNFAIP3	FHEAKRTKE	LUNG	686	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
TNFAIP3	FKRTAAEAS	LUNG	540	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	3	0	3	N
TNFAIP3	FLFSETTTM	LARGE_INTESTINE	468	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	12	0	15	N
TNFAIP3	FLSVNTQPL	LUNG	395	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	15	0	7	N
TNFAIP3	FLTDHENEM	LARGE_INTESTINE	290	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	Y	7	9	1	N
TNFAIP3	FQNTILCLG	LUNG	651	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	2	0	0	N
TNFAIP3	FSETTTMKC	LARGE_INTESTINE	470	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	4	0	2	N
TNFAIP3	FSTIKETDT	LARGE_INTESTINE	127	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	2	0	0	N
TNFAIP3	FTEAQNQRF	LUNG	678	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	6	0	0	N
TNFAIP3	GIIHYFKTM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	35	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	Y	4	9	0	N
TNFAIP3	GPEELPGMA	SKIN	426	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	5	0	0	N
TNFAIP3	GPHSAPPTT	LARGE_INTESTINE	456	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	4	0	0	N
TNFAIP3	GTTYLINAA	LUNG	320	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	2	0	0	N
TNFAIP3	GWDHGTTYL	LUNG	316	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	Y	5	10	0	N
TNFAIP3	GYCNECFKF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	777	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	4	0	0	N
TNFAIP3	GYCQKCFTE	LUNG	672	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	0	0	0	N
TNFAIP3	HATSQHMWG	ENDOMETRIUM	106	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	HCRAPACDH	LUNG	761	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	0	0	0	N
TNFAIP3	HEAKRTKEQ	LUNG	687	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
TNFAIP3	HENEMKEKL	LARGE_INTESTINE	294	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	Y	9	10	0	N
TNFAIP3	HFASASGKV	LUNG	636	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	2	0	0	N
TNFAIP3	HFLTDHENE	LARGE_INTESTINE	289	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
TNFAIP3	HGTTYLINA	LUNG	319	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	2	0	0	N
TNFAIP3	HMWGVQDTD	ENDOMETRIUM	111	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	HQCSERRQK	URINARY_TRACT	405	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	1	0	0	N
TNFAIP3	HQHSKSDPS	LARGE_INTESTINE	560	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	1	0	0	N
TNFAIP3	HSAPPTTPS	LARGE_INTESTINE	458	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
TNFAIP3	HSKSDPSRL	LARGE_INTESTINE	562	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	Y	6	10	0	N
TNFAIP3	HYFKTMHRY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	38	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	Y	4	11	0	N
TNFAIP3	IFEPTNGII	ENDOMETRIUM	29	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	Y	8	12	0	N
TNFAIP3	IHYFKTMHR	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	37	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	Y	1	10	26	N
TNFAIP3	IIHYFKTMH	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	36	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	N	0	0	10	N
TNFAIP3	IKETDTRNF	LARGE_INTESTINE	130	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	3	0	1	N
TNFAIP3	ILCLGRECG	LUNG	655	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	0	0	0	N
TNFAIP3	KALFSTIKE	LARGE_INTESTINE	124	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	0	0	0	N
TNFAIP3	KCFTEAQNQ	LUNG	676	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	0	0	0	N
TNFAIP3	KEQLRSSQR	LUNG	693	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	Y
TNFAIP3	KETDTCNFK	LUNG	131	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	Y	2	11	0	N
TNFAIP3	KHFASASGK	LUNG	635	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	0	0	0	N
TNFAIP3	KKLSWCREV	ENDOMETRIUM	81	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	4	0	0	N
TNFAIP3	KLNSKSGPE	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	420	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	1	0	0	N
TNFAIP3	KLPKLNSKS	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	417	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	1	0	0	N
TNFAIP3	KLSWCREVR	ENDOMETRIUM	82	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	Y	7	9	0	N
TNFAIP3	KLVVLKTNG	STOMACH	91	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	0	0	0	N
TNFAIP3	KPGPEELPG	SKIN	424	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	1	0	0	N
TNFAIP3	KPTNGIIHY	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	31	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	Y	13	10	0	N
TNFAIP3	KQHCRAPAC	LUNG	759	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	4	0	0	N
TNFAIP3	KRTAAEASS	LUNG	541	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	2	0	0	N
TNFAIP3	KRTKEQLRS	LUNG	690	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	2	0	0	N
TNFAIP3	KSDPSPLVR	LUNG	564	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	5	0	0	N
TNFAIP3	KSGPEGLPG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	424	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	2	0	0	Y
TNFAIP3	KVHFLTDHE	LARGE_INTESTINE	287	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
TNFAIP3	LCHQCSERR	URINARY_TRACT	403	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	3	0	0	N
TNFAIP3	LCLGRECGT	LUNG	656	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	1	0	0	N
TNFAIP3	LESQKKLSW	ENDOMETRIUM	77	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	7	0	0	N
TNFAIP3	LFSETTTMK	LARGE_INTESTINE	469	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	1	0	5	N
TNFAIP3	LFSTIKETD	LARGE_INTESTINE	126	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	0	0	0	N
TNFAIP3	LKETDTCNF	LUNG	130	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	3	0	1	N
TNFAIP3	LKVHFLTDH	LARGE_INTESTINE	286	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	1	0	7	N
TNFAIP3	LMHATSQHM	ENDOMETRIUM	104	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	6	0	6	N
TNFAIP3	LNSKPGPEE	SKIN	421	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	0	0	2	N
TNFAIP3	LNSKSGPEG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	421	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	0	0	0	N
TNFAIP3	LPKLNSKSG	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	418	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	1	0	0	N
TNFAIP3	LPPSCHQHS	LARGE_INTESTINE	555	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	4	0	0	N
TNFAIP3	LRKALFSTI	LARGE_INTESTINE	122	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	Y	5	10	2	N
TNFAIP3	LSVNTQPLC	LUNG	396	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	1	0	0	N
TNFAIP3	LSWCREVRK	ENDOMETRIUM	83	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	Y	3	20	0	N
TNFAIP3	LTDHENEMK	LARGE_INTESTINE	291	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	2	0	0	N
TNFAIP3	LVNRDWGRF	OESOPHAGUS	275	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	3	0	4	Y
TNFAIP3	LVRSPSPPS	KIDNEY	570	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	31	N
TNFAIP3	LVVLKTNGD	STOMACH	92	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	0	0	27	N
TNFAIP3	MHATSQHMW	ENDOMETRIUM	105	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	3	0	0	N
TNFAIP3	NCPFFLSVN	LUNG	391	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	0	0	0	N
TNFAIP3	NECFKFKQM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	780	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	7	0	0	N
TNFAIP3	NGIIHYFKT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	34	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	N	3	0	0	N
TNFAIP3	NGYCNECFK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	776	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	1	0	0	N
TNFAIP3	NKHFASASG	LUNG	634	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	0	0	0	N
TNFAIP3	NRDWGRFED	OESOPHAGUS	277	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	1	0	0	Y
TNFAIP3	NSKPGPEEL	SKIN	422	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	Y	7	9	0	N
TNFAIP3	NSKSGPEGL	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	422	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	Y	7	10	0	N
TNFAIP3	NTILCLGRE	LUNG	653	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	0	0	0	N
TNFAIP3	NTQPLCHQC	URINARY_TRACT	399	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	1	0	0	N
TNFAIP3	PEDIFEPTN	ENDOMETRIUM	26	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	0	0	0	N
TNFAIP3	PEDPPKQHC	LUNG	754	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	0	0	0	N
TNFAIP3	PEELPGMAL	SKIN	427	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	2	0	0	N
TNFAIP3	PFFLSVNTQ	LUNG	393	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	0	0	0	N
TNFAIP3	PFLFSETTT	LARGE_INTESTINE	467	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
TNFAIP3	PGPEELPGM	SKIN	425	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	1	0	0	N
TNFAIP3	PHSAPPTTP	LARGE_INTESTINE	457	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
TNFAIP3	PKLNSKSGP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	419	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	0	0	0	Y
TNFAIP3	PKQHCRAPA	LUNG	758	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	1	0	0	N
TNFAIP3	PLCHQCSER	URINARY_TRACT	402	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	0	0	0	N
TNFAIP3	PLVNRDWGR	OESOPHAGUS	274	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	2	0	0	N
TNFAIP3	PLVRSPSPH	LUNG	569	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	0	0	0	N
TNFAIP3	PNCPFFLSV	LUNG	390	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	Y	2	12	0	N
TNFAIP3	PPKQHCRAP	LUNG	757	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	1	0	0	N
TNFAIP3	PPSCHQHSK	LARGE_INTESTINE	556	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
TNFAIP3	PPSCHRAGN	KIDNEY	576	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	0	N
TNFAIP3	PPTTPSPFL	LARGE_INTESTINE	461	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	10	0	0	N
TNFAIP3	PSCHQHSKS	LARGE_INTESTINE	557	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
TNFAIP3	PSCHRAGND	KIDNEY	577	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	0	N
TNFAIP3	PSPLVRSPS	LUNG	567	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	0	0	0	N
TNFAIP3	PSPPSCHRA	KIDNEY	574	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	0	Y
TNFAIP3	PTNGIIHYF	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	32	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	N	1	0	0	N
TNFAIP3	PTTPSPFLF	LARGE_INTESTINE	462	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	2	0	0	N
TNFAIP3	QCSERRQKN	URINARY_TRACT	406	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	1	0	0	N
TNFAIP3	QGWDHGTTY	LUNG	315	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	6	0	0	N
TNFAIP3	QHCRAPACD	LUNG	760	p.R761H	c.2282G>A	Missense_Mutation	1	0.11	NCIH2171	N	0	0	0	N
TNFAIP3	QHMWGVQDT	ENDOMETRIUM	110	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	2	0	0	N
TNFAIP3	QHSKSDPSR	LARGE_INTESTINE	561	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	1	0	0	N
TNFAIP3	QKCFTEAQN	LUNG	675	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	1	0	0	N
TNFAIP3	QKKLSWCRE	ENDOMETRIUM	80	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	QNTILCLGR	LUNG	652	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	2	0	0	N
TNFAIP3	QPLCHQCSE	URINARY_TRACT	401	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	0	0	0	N
TNFAIP3	QRSKSDPSP	LUNG	561	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	1	0	0	N
TNFAIP3	RDWGRFEDL	OESOPHAGUS	278	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	Y	9	11	0	N
TNFAIP3	RENKHFASA	LUNG	632	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	6	0	0	N
TNFAIP3	REVRKLVVL	STOMACH	87	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	13	0	0	N
TNFAIP3	RFHEAKRTK	LUNG	685	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
TNFAIP3	RFQNTILCL	LUNG	650	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	8	0	0	N
TNFAIP3	RKALFSTIK	LARGE_INTESTINE	123	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	1	0	0	N
TNFAIP3	RKLVVLKTN	STOMACH	90	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	1	0	0	N
TNFAIP3	RLVRSPSPP	KIDNEY	569	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	1	0	0	N
TNFAIP3	RSKSDPSPL	LUNG	562	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	8	0	0	N
TNFAIP3	RSPSPPSCH	KIDNEY	572	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	0	N
TNFAIP3	RTAAEASSS	LUNG	542	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	1	0	0	Y
TNFAIP3	RTKEQLRSS	LUNG	691	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	1	0	0	N
TNFAIP3	RTPEDIFEP	ENDOMETRIUM	24	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	1	0	0	N
TNFAIP3	SAPPTTPSP	LARGE_INTESTINE	459	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
TNFAIP3	SASGKVSPT	LUNG	639	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	4	0	0	N
TNFAIP3	SCHQHSKSD	LARGE_INTESTINE	558	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
TNFAIP3	SDPSPLVRS	LUNG	565	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	3	0	0	N
TNFAIP3	SETTTMKCR	LARGE_INTESTINE	471	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
TNFAIP3	SGPEGLPGM	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	425	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	8	0	0	N
TNFAIP3	SKPGPEELP	SKIN	423	p.G429E	c.1286G>A	Missense_Mutation	1	0.11	CHL1	N	0	0	0	N
TNFAIP3	SKSDPSPLV	LUNG	563	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	2	0	0	N
TNFAIP3	SKSGPEGLP	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	423	p.P425S	c.1273C>T	Missense_Mutation	1	0.11	MUTZ3	N	0	0	0	N
TNFAIP3	SLPPSCHQH	LARGE_INTESTINE	554	p.R562H	c.1685G>A	Missense_Mutation	1	0.11	LS180	N	0	0	0	N
TNFAIP3	SPLVRSPSP	LUNG	568	p.R569P	c.1706G>C	Missense_Mutation	1	0.11	NCIH510	N	0	0	0	N
TNFAIP3	SPPSCHRAG	KIDNEY	575	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	0	0	0	N
TNFAIP3	SPSPPSCHR	KIDNEY	573	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	3	0	0	N
TNFAIP3	SQHMWGVQD	ENDOMETRIUM	109	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	SQKKLSWCR	ENDOMETRIUM	79	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	7	0	0	N
TNFAIP3	SRFQNTILC	LUNG	649	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	4	0	0	N
TNFAIP3	STCFKRTAA	LUNG	537	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	1	0	0	N
TNFAIP3	STIKETDTR	LARGE_INTESTINE	128	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	5	0	0	N
TNFAIP3	STLKETDTC	LUNG	128	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	1	0	0	Y
TNFAIP3	SWCREVRKL	ENDOMETRIUM	84	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	Y	4	12	0	N
TNFAIP3	TAAEASSSL	LUNG	543	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	13	0	0	N
TNFAIP3	TCFKRTAAE	LUNG	538	p.T544A	c.1630A>G	Missense_Mutation	1	0.11	HCC1359	N	0	0	0	N
TNFAIP3	TCNFKFRWQ	LUNG	135	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	0	0	0	N
TNFAIP3	TDHENEMKE	LARGE_INTESTINE	292	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	0	0	0	N
TNFAIP3	TDTCNFKFR	LUNG	133	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	1	0	0	N
TNFAIP3	TEAQNQRFH	LUNG	679	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	0	0	0	N
TNFAIP3	TIKETDTRN	LARGE_INTESTINE	129	p.L130I	c.388C>A	Missense_Mutation	1	0.11	SW48	N	0	0	0	N
TNFAIP3	TILCLGREC	LUNG	654	p.P656L	c.1967C>T	Missense_Mutation	1	0.11	NCIH2106	N	0	0	0	N
TNFAIP3	TKEQLRSSQ	LUNG	692	p.E693K	c.2077G>A	Missense_Mutation	1	0.11	NCIH1944	N	0	0	0	Y
TNFAIP3	TLESQKKLS	ENDOMETRIUM	76	p.N84S	c.251A>G	Missense_Mutation	1	0.11	EN	N	1	0	0	N
TNFAIP3	TLKETDTCN	LUNG	129	p.R136C	c.406C>T	Missense_Mutation	1	0.11	NCIH460	N	0	0	0	N
TNFAIP3	TMKCRSPGC	LARGE_INTESTINE	475	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	1	0	0	N
TNFAIP3	TNGIIHYFK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	33	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	N	0	0	0	N
TNFAIP3	TPEDIFEPT	ENDOMETRIUM	25	p.K31E	c.91A>G	Missense_Mutation	1	0.11	HEC108	N	2	0	0	N
TNFAIP3	TPNCPFFLS	LUNG	389	p.M396L	c.1186A>T	Missense_Mutation	1	0.11	NCIH1781	N	3	0	0	N
TNFAIP3	TPSPFLFSE	LARGE_INTESTINE	464	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	0	0	0	N
TNFAIP3	TQPLCHQCS	URINARY_TRACT	400	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	0	0	0	N
TNFAIP3	TSQHMWGVQ	ENDOMETRIUM	108	p.Y111H	c.331T>C	Missense_Mutation	1	0.11	EN	N	0	0	0	N
TNFAIP3	TTMKCRSPG	LARGE_INTESTINE	474	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
TNFAIP3	TTPSPFLFS	LARGE_INTESTINE	463	p.A464T	c.1390G>A	Missense_Mutation	1	0.11	SNU1040	N	1	0	0	N
TNFAIP3	TTTMKCRSP	LARGE_INTESTINE	473	p.A475T	c.1423G>A	Missense_Mutation	1	0.11	HCT15	N	0	0	0	N
TNFAIP3	TTYLINAAK	LUNG	321	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	Y	5	12	0	N
TNFAIP3	TYLINAAKL	LUNG	322	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	Y	8	12	0	N
TNFAIP3	VHFLTDHEN	LARGE_INTESTINE	288	p.P294H	c.881C>A	Missense_Mutation	1	0.11	HRT18	N	1	0	0	N
TNFAIP3	VLKTNGDGN	STOMACH	94	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	0	0	0	Y
TNFAIP3	VNRDWGRFE	OESOPHAGUS	276	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	0	0	0	Y
TNFAIP3	VNTQPLCHQ	URINARY_TRACT	398	p.E406Q	c.1216G>C	Missense_Mutation	1	0.11	5637	N	0	0	4	N
TNFAIP3	VPLVNRDWG	OESOPHAGUS	273	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	2	0	0	N
TNFAIP3	VRKLVVLKT	STOMACH	89	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	2	0	44	N
TNFAIP3	VRSPSPPSC	KIDNEY	571	p.H577P	c.1730A>C	Missense_Mutation	1	0.11	TUHR10TKB	N	2	0	1	N
TNFAIP3	VVLKTNGDG	STOMACH	93	p.A94V	c.281C>T	Missense_Mutation	1	0.11	TGBC11TKB	N	0	0	5	N
TNFAIP3	WDHGTTYLI	LUNG	317	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	7	0	0	N
TNFAIP3	WGRFEDLKV	OESOPHAGUS	280	p.R280W	c.838C>T	Missense_Mutation	1	0.11	TT	N	7	0	3	N
TNFAIP3	YCNECFKFK	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	778	p.Q784K	c.2350C>A	Missense_Mutation	1	0.11	SUPT11	N	3	0	0	N
TNFAIP3	YCQKCFTEA	LUNG	673	p.I679T	c.2036T>C	Missense_Mutation	1	0.11	NCIH1184	N	4	0	0	N
TNFAIP3	YFKTMHRYT	HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	39	p.H39Y	c.115C>T	Missense_Mutation	1	0.11	DND41	N	3	0	0	N
TNFAIP3	YLINAAKLD	LUNG	323	p.H323Y	c.967C>T	Missense_Mutation	1	0.11	NCIH647	N	2	0	6	N
TNFAIP3	YRENKHFAS	LUNG	631	p.A639S	c.1915G>T	Missense_Mutation	1	0.11	SCLC21H	N	4	0	8	N
TNFAIP3	ASGKVSPTS	LARGE_INTESTINE	640	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	1	0	0	N
TNFAIP3	ASGKVSPTS	LARGE_INTESTINE	640	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	1	0	0	N
TNFAIP3	CFKRTTVEA	LUNG	539	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	1	0	0	N
TNFAIP3	CFKRTTVEA	LARGE_INTESTINE	539	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	1	0	0	N
TNFAIP3	DPSWLVRSP	SKIN	566	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	0	0	0	N
TNFAIP3	DPSWLVRSP	LARGE_INTESTINE	566	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	0	0	0	N
TNFAIP3	FKRTTVEAS	LUNG	540	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	3	0	13	N
TNFAIP3	FKRTTVEAS	LARGE_INTESTINE	540	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	3	0	13	N
TNFAIP3	GKVSPTSSR	LARGE_INTESTINE	642	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	1	0	0	N
TNFAIP3	GKVSPTSSR	LARGE_INTESTINE	642	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	1	0	0	N
TNFAIP3	KRTTVEASS	LUNG	541	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	2	0	0	Y
TNFAIP3	KRTTVEASS	LARGE_INTESTINE	541	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	2	0	0	Y
TNFAIP3	KSDPSWLVR	SKIN	564	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	5	0	0	N
TNFAIP3	KSDPSWLVR	LARGE_INTESTINE	564	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	5	0	0	N
TNFAIP3	KVSPTSSRF	LARGE_INTESTINE	643	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	7	0	0	N
TNFAIP3	KVSPTSSRF	LARGE_INTESTINE	643	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	7	0	0	N
TNFAIP3	PSWLVRSPS	SKIN	567	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	0	0	0	N
TNFAIP3	PSWLVRSPS	LARGE_INTESTINE	567	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	0	0	0	N
TNFAIP3	PTSSRFQNT	LARGE_INTESTINE	646	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	0	0	0	N
TNFAIP3	PTSSRFQNT	LARGE_INTESTINE	646	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	0	0	0	N
TNFAIP3	QRSKSDPSW	SKIN	561	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	2	0	0	N
TNFAIP3	QRSKSDPSW	LARGE_INTESTINE	561	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	2	0	0	N
TNFAIP3	RSKSDPSWL	SKIN	562	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	Y	8	10	0	N
TNFAIP3	RSKSDPSWL	LARGE_INTESTINE	562	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	Y	8	10	0	N
TNFAIP3	RTTVEASSS	LUNG	542	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	1	0	0	Y
TNFAIP3	RTTVEASSS	LARGE_INTESTINE	542	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	1	0	0	Y
TNFAIP3	SDPSWLVRS	SKIN	565	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	3	0	0	N
TNFAIP3	SDPSWLVRS	LARGE_INTESTINE	565	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	3	0	0	N
TNFAIP3	SGKVSPTSS	LARGE_INTESTINE	641	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	1	0	0	N
TNFAIP3	SGKVSPTSS	LARGE_INTESTINE	641	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	1	0	0	N
TNFAIP3	SKSDPSWLV	SKIN	563	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	2	0	0	N
TNFAIP3	SKSDPSWLV	LARGE_INTESTINE	563	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	2	0	0	N
TNFAIP3	SPTSSRFQN	LARGE_INTESTINE	645	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	3	0	0	N
TNFAIP3	SPTSSRFQN	LARGE_INTESTINE	645	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	3	0	0	N
TNFAIP3	SSRFQNTIP	LARGE_INTESTINE	648	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	0	0	0	N
TNFAIP3	SSRFQNTIP	LARGE_INTESTINE	648	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	0	0	0	N
TNFAIP3	STCFKRTTV	LUNG	537	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	Y	2	9	0	N
TNFAIP3	STCFKRTTV	LARGE_INTESTINE	537	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	Y	2	9	0	N
TNFAIP3	SWLVRSPSP	SKIN	568	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	0	0	0	N
TNFAIP3	SWLVRSPSP	LARGE_INTESTINE	568	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	0	0	0	N
TNFAIP3	TCFKRTTVE	LUNG	538	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	0	0	0	N
TNFAIP3	TCFKRTTVE	LARGE_INTESTINE	538	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	0	0	0	N
TNFAIP3	TSSRFQNTI	LARGE_INTESTINE	647	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	Y	5	10	0	N
TNFAIP3	TSSRFQNTI	LARGE_INTESTINE	647	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	Y	5	10	0	N
TNFAIP3	TTVEASSSL	LUNG	543	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	15	0	0	Y
TNFAIP3	TTVEASSSL	LARGE_INTESTINE	543	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	15	0	0	Y
TNFAIP3	TVEASSSLS	LUNG	544	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	1	0	0	N
TNFAIP3	TVEASSSLS	LARGE_INTESTINE	544	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	1	0	0	N
TNFAIP3	VEASSSLST	LUNG	545	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	NCIH2141	N	5	0	0	N
TNFAIP3	VEASSSLST	LARGE_INTESTINE	545	p.A545V	c.1634C>T	Missense_Mutation	1	0.22	SW948	N	5	0	0	N
TNFAIP3	VSPTSSRFQ	LARGE_INTESTINE	644	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HCT15	N	0	0	1	N
TNFAIP3	VSPTSSRFQ	LARGE_INTESTINE	644	p.A648S	c.1942G>T	Missense_Mutation	1	0.22	HRT18	N	0	0	1	N
TNFAIP3	WLVRSPSPH	SKIN	569	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	HS895T	N	1	0	8	N
TNFAIP3	WLVRSPSPH	LARGE_INTESTINE	569	p.R569W	c.1705C>T	Missense_Mutation	1	0.22	SNU81	N	1	0	8	N