Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

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The result page of search shows exclusive peptide/epitopes generated due to mutation [Neoepitope], the tissue of origin [Tissue], position of peptide in protein [Position], number of mismatches counted by aligning mutated and normal protein sequence [Num Mismatch, percentage of cell lines with this peptide over total number of cell lines [Promiscuity %]. The immune information include CTL epitopes (Yes/No), MHC I binders, MHC II binders (both given as number of alleles) and B cell epitopes (Yes/No). For more information, please click HERE


Result Reset Search:
ProteinNeoepitopesTissuePositionProt MutationcDNA MutationMutation TypeNum MismatchPromiscuity (%)Cell LineCTLMHC INHLApredMHC IIBcell
VHLDIVRSLYEIKIDNEY179p.E186fsc.557_557delAFrame_Shift_Del10.11TUHR10TKBN700N
VHLDSLFLPISHKIDNEY143p.V142fsc.426_429delTGACFrame_Shift_Del60.11A498N100N
VHLEIWKTTQMCKIDNEY186p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLEMPPGCPEPKIDNEY160p.E160fsc.480_481delGCFrame_Shift_Del40.11VMRCRCWN000N
VHLFLPISHCQCKIDNEY146p.V142fsc.426_429delTGACFrame_Shift_Del70.11A498N504N
VHLFVPSLNVDSKIDNEY136p.V142fsc.426_429delTGACFrame_Shift_Del10.11A498N3026N
VHLIVRSLYEIWKIDNEY180p.E186fsc.557_557delAFrame_Shift_Del20.11TUHR10TKBN401N
VHLIWKTTQMCRKIDNEY187p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN200N
VHLKEMPPGCPEKIDNEY159p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN200N
VHLKTTQMCRKTKIDNEY189p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLLFLPISHCQKIDNEY145p.V142fsc.426_429delTGACFrame_Shift_Del60.11A498N001N
VHLLKEMPPGCPKIDNEY158p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN000N
VHLLNVDSLFLPKIDNEY140p.V142fsc.426_429delTGACFrame_Shift_Del50.11A498N004N
VHLLPISHCQCIKIDNEY147p.V142fsc.426_429delTGACFrame_Shift_Del60.11A498N1404N
VHLLPVYTLKEMKIDNEY153p.E160fsc.480_481delGCFrame_Shift_Del10.11VMRCRCWN1300N
VHLLYEIWKTTQKIDNEY184p.E186fsc.557_557delAFrame_Shift_Del60.11TUHR10TKBN000N
VHLMPPGCPEPSKIDNEY161p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN500N
VHLNVDSLFLPIKIDNEY141p.V142fsc.426_429delTGACFrame_Shift_Del50.11A498N200N
VHLPGCPEPSQAKIDNEY163p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN000N
VHLPISHCQCILKIDNEY148p.V142fsc.426_429delTGACFrame_Shift_Del70.11A498N000N
VHLPPGCPEPSQKIDNEY162p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN000N
VHLPSLNVDSLFKIDNEY138p.V142fsc.426_429delTGACFrame_Shift_Del30.11A498N100N
VHLPVYTLKEMPKIDNEY154p.E160fsc.480_481delGCFrame_Shift_Del20.11VMRCRCWN000N
VHLQMCRKTWSGKIDNEY192p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN000N
VHLRSLYEIWKTKIDNEY182p.E186fsc.557_557delAFrame_Shift_Del40.11TUHR10TKBN100N
VHLSLFLPISHCKIDNEY144p.V142fsc.426_429delTGACFrame_Shift_Del60.11A498N500N
VHLSLNVDSLFLKIDNEY139p.V142fsc.426_429delTGACFrame_Shift_Del40.11A498Y11110N
VHLSLYEIWKTTKIDNEY183p.E186fsc.557_557delAFrame_Shift_Del50.11TUHR10TKBN400N
VHLTLKEMPPGCKIDNEY157p.E160fsc.480_481delGCFrame_Shift_Del50.11VMRCRCWN200N
VHLTQMCRKTWSKIDNEY191p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN000N
VHLTTQMCRKTWKIDNEY190p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN100N
VHLVDSLFLPISKIDNEY142p.V142fsc.426_429delTGACFrame_Shift_Del50.11A498N100N
VHLVPSLNVDSLKIDNEY137p.V142fsc.426_429delTGACFrame_Shift_Del20.11A498N1800N
VHLVRSLYEIWKKIDNEY181p.E186fsc.557_557delAFrame_Shift_Del30.11TUHR10TKBN206Y
VHLVYTLKEMPPKIDNEY155p.E160fsc.480_481delGCFrame_Shift_Del30.11VMRCRCWN000N
VHLWKTTQMCRKKIDNEY188p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN302N
VHLYEIWKTTQMKIDNEY185p.E186fsc.557_557delAFrame_Shift_Del70.11TUHR10TKBN10015N
VHLYTLKEMPPGKIDNEY156p.E160fsc.480_481delGCFrame_Shift_Del40.11VMRCRCWN100N
VHLANITPPVYTKIDNEY149p.L153Pc.458T>CMissense_Mutation10.11TUHR14TKBN100N
VHLDLEWLTQERLUNG197p.R200Wc.598C>TMissense_Mutation10.11HCC4006N600N
VHLDNYRRLDIVENDOMETRIUM173p.E173Dc.519G>TMissense_Mutation10.11JHUEM7N700N
VHLENYKRLDIVENDOMETRIUM173p.R176Kc.527G>AMissense_Mutation10.11TENN700N
VHLEWLTQERIALUNG199p.R200Wc.598C>TMissense_Mutation10.11HCC4006N000N
VHLFANITPPVYKIDNEY148p.L153Pc.458T>CMissense_Mutation10.11TUHR14TKBN804N
VHLGQLWLFRDAKIDNEY114p.H115Qc.345C>AMissense_Mutation10.11SNU1272N100N
VHLHSYRGQLWLKIDNEY110p.H115Qc.345C>AMissense_Mutation10.11SNU1272Y17100N
VHLIFANITPPVKIDNEY147p.L153Pc.458T>CMissense_Mutation10.11TUHR14TKBN300N
VHLIHSYRGQLWKIDNEY109p.H115Qc.345C>AMissense_Mutation10.11SNU1272N300N
VHLITPPVYTLKKIDNEY151p.L153Pc.458T>CMissense_Mutation10.11TUHR14TKBY4130N
VHLKDLEWLTQELUNG196p.R200Wc.598C>TMissense_Mutation10.11HCC4006N000N