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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) GC Content (%) Cell line PubMed 1388 HIV-1 (LAI) K02013 LTR N/A AGAUGGGUGCGAGAGCGUU 66.00 46 293 T 18346971 1417 HIV-1 (LAI) K02013 Pol 4545 GUGAAGGGGCAGUAGUAAU 66.00 38 293 T 19384894 1437 HIV-1 (NL4-3) AF324493 Gag 534 AGCCACCCCACAAGAUUUAAA 66.40 35 HEK 293a 19497094 1235 HIV-1 (NL4-3) AF324493 LTR 515 UGCUUAAGCCUCAAUAAAGCU 66.70 31 Hela 17996047 1431 HIV-1 (NL4-3) AF324493 LTR 553 GUAGUGUGUGCCCGUCUGUU 67.00 44 HEK 293a 19497094 1571 HIV-1 (NL4-3) AF324493 Gag 2062 GAUUGUACUGAGAGACAGGCU 67.00 38 SupT 18727943 1123 HIV-1 (LAI) K02013 Gag 331 GAGAGAUGGGUGCGAGAGC 67.00 50 293 T 16959541 1002 HIV-1 (NL4-3) AF324493 Tat/Rev 5982 GCGGAGACAGCGACGAAGAGC 67.00 54 293T/EcR 11981565 1278 95MM-yIDU106 N/A LTR 689 ACGCAGGACUCGGCUUGCUGA 67.20 50 Hela 17996047 1508 HIV-1 (NL4-3) AF324493 Env 1432 AGAAGUGAAUUAUAUAAAUAU 68.00 12 HEK 293a 19497094 1028 HIV-1 (NL4-3) AF324493 Tat/Rev 2960 UGAGACACCAGGGAUUAGA 68.00 38 293 T 12438622 1020 HIV-1 (NL4-3) AF324493 Tat/Rev 2960 UGAGACACCAGGGAUUAGA 68.00 38 jurkat 12438622 1416 HIV-1 (LAI) K02013 Pol 4543 AGGUGAAGGGGCAGUAGUA 68.00 42 293 T 19384894 1058 HIV-1 (NL4-3) AF324493 Env 8749 AAGAAUAAGACAGGGCUUGGA 69.00 35 293 T 15564478 1673 HIV NL4-3/M184V AF324493 Tat/Rev NA UAUCAAUACGUGGAUGAUUUGUAU 69.00 24 Hela 16290277 1476 HIV-1 (NL4-3) AF324493 Vif 12 AUGGCAGGUGAUGAUUGUGU 69.20 36 HEK 293a 19497094 1099 HIV-1 HXB2 K03455 Nef 8914 CAUGGAGCAAUCACAAGUA 70.00 33 U87-CD4 16378959 1533 HIV-1 (LAI) K02013 Pol 4545 GUGAAGGGGCAGUAGUAAU 70.00 38 293 T 20188764 1113 HIV-1 (NL4-3) AF324493 Nef 9147 UUCCCUGAUUGGCAGAACUACACAC 70.00 40 U937 16857988

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