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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) Target Conservation * Cell line PubMed 1013 HIV-1 (IIIB) EU541617 Gag K*1475 GAGAACCAAGGGGAAGUGACA 75.00 711(47.53%) 293 T 12391237 1014 HIV-1 (IIIB) EU541617 Gag K*896 GGGCAAGCAGGGAGCUAGAAC 89.00 331(22.13%) 293 T 12391237 1003 HIV-1 (IIIB) EU541617 Gag 1608 GAUUGUACUGAGAGACAGGCU 76.00 183(12.23%) Hela 12042777 1015 HIV-1 (IIIB) EU541617 LTR K*9215 GAUGGUGCUACAAGCUAGUAC 94.00 50(3.34%) 293 T 12391237 1063 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGGCAAGUGGUCAAAACGUA 48.30 0(0.00%) MT-4 T/Jurkat T 15601474 1064 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGCCAGCAGCAGAUGGGGUG 36.50 1(0.07%) MT-4 T/Jurkat T 15601474 1065 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGUGCCUGGCUAGAAGCACA 78.40 1(0.07%) MT-4 T/Jurkat T 15601474 1066 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGCACAAGAGGAGGAGA 70.90 0(0.00%) MT-4 T/Jurkat T 15601474 1067 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGACUGGAAGGGCUAAUUUG 50.50 0(0.00%) MT-4 T/Jurkat T 15601474 1068 HIV-1 (IIIB) EU541617 Nef N/A GCUCGACGGCUACUUCCCUGAUUGGC 65.50 0(0.00%) MT-4 T/Jurkat T 15601474 1069 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGGUAGAAGAGGCCAAUGAA 58.00 0(0.00%) MT-4 T/Jurkat T 15601474 1070 HIV-1 (IIIB) EU541617 Nef N/A GCGUCGACGCAUUUCAUCACAUGGCCC 48.30 2(0.13%) MT-4 T/Jurkat T 15601474 1525 HIV-1 (IIIB) EU541617 LTR N/A GGGACUUUCCGCUGGGGAC 0.00 438(29.28%) MAGIC-5 19771207 1585 HIV-1 (IIIB) EU541617 Gag K*2062 GAUUGUACUGAGAGACAGG 88.00 197(13.17%) Hela 15831707 1575 HIV-1 (IIIB) EU541617 vif K*5195 GUUCAGAAGUACACAUCCC 80.00 797(53.28%) Hela 15831707 1574 HIV-1 (IIIB) EU541617 Gag K*2062 GAUUGUACUGAGAGACAGG 91.00 197(13.17%) Hela 15831707 1573 HIV-1 (IIIB) EU541617 rev K*8485 GGCACUUAUCUGGGACGAU 96.00 2(0.13%) Hela 15831707

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