References for PCMdb

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S. No. Title PMID
1Preliminary study analyzing the methylated genes in the plasma of patients with pancreatic cancer.22414467
2Reduced levels of p15INK4b, p16INK4a, p21cip1 and p27kip1 in pancreatic carcinoma.22293850
3Genome-wide CpG island profiling of intraductal papillary mucinous neoplasms of the pancreas.22173550
4Dickkopf3 overexpression inhibits pancreatic cancer cell growth in vitro.21987623
5Genome-wide analysis of promoter methylation associated with gene expression profile in pancreatic adenocarcinoma.21610144
6Analysis of LKB1 mutations and other molecular alterations in pancreatic acinar cell carcinoma.21572398
7Aberrant methylation frequency of TNFRSF10C promoter in pancreatic cancer cell lines.21269942
8SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma.20939879
9DNA methylation and histone H3-K9 modifications contribute to MUC17 expression.20926598
10Epigenetic regulation affects N-myc downstream-regulated gene 1 expression indirectly in pancreatic cancer cells.20173668
11Syk tyrosine kinase acts as a pancreatic adenocarcinoma tumor suppressor by regulating cellular growth and invasion.19893036
12Unique methylation pattern of oncostatin m receptor gene in cancers of colorectum and other digestive organs.19223499
13Epigenetic regulation and molecular characterization of C/EBPalpha in pancreatic cancer cells.19035457
14DNA methylation alterations in endoscopic retrograde cholangiopancreatography brush samples of patients with suspected pancreaticobiliary disease.18995218
15Multiple genes are hypermethylated in intraductal papillary mucinous neoplasms of the pancreas.18820670
16Genome-wide profiling of methylated promoters in pancreatic adenocarcinoma.18535405
17Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancer.18528941
18Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases.18492726
19Adverse prognosis of epigenetic inactivation in RUNX3 gene at 1p36 in human pancreatic cancer.18475302
20MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells.18413738
21Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.18223216
22CpG island methylation profile of pancreatic intraepithelial neoplasia.18157091
23Molecular consequences of SOD2 expression in epigenetically silenced pancreatic carcinoma cell lines.17895890
24Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.17675336
25DNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.16537562
26Epigenetic inactivation of TCF2 in ovarian cancer and various cancer cell lines.16479257
27DNA methylation alterations in the pancreatic juice of patients with suspected pancreatic disease.16424060
28Epigenetic alterations in neuroendocrine tumors: methylation of RAS-association domain family 1, isoform A and p16 genes are associated with metastasis.16258509
29Alterations of tumor suppressor gene p16INK4a in pancreatic ductal carcinoma.15985168
30Aberrant methylation of the Human Hedgehog interacting protein (HHIP) gene in pancreatic neoplasms.15970691
31The chemokine receptor CXCR4 is regulated by DNA methylation in pancreatic cancer.15662133
32Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types.15383627
33Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.15289340
34Hypermethylation-associated inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human pancreatic cancers.15121754
35The tumor suppressor gene WWOX at FRA16D is involved in pancreatic carcinogenesis.15073125
36Ubiquitous aberrant RASSF1A promoter methylation in childhood neoplasia.14871978
37CpG methylation and transcription factors Sp1 and Sp3 regulate the expression of the human secretin receptor gene.14645499
38Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas.14614047
39Aberrant hypermethylation of tumor suppressor genes in pancreatic endocrine neoplasms.14501508
40Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.12874021
41Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms.12865927
42Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays.12839967
43O6-methyl-guanine-DNA methyltransferase methylation in serum and tumor DNA predicts response to 1,3-bis(2-chloroethyl)-1-nitrosourea but not to temozolamide plus cisplatin in glioblastoma multiforme.12684420
44Significance of thymidylate synthase activity in renal cell carcinoma.12684419
45Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues.12684418
46Diagnosing pancreatic cancer using methylation specific PCR analysis of pancreatic juice.12673124
47Exploration of global gene expression patterns in pancreatic adenocarcinoma using cDNA microarrays.12651607
48Frequent methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene in pancreatic endocrine tumors.12629131
49Methylation status of p14ARF and p16INK4a as detected in pancreatic secretions.12610506
50Effects of 5-aza-2'-deoxycytidine on matrix metalloproteinase expression and pancreatic cancer cell invasiveness.12591989

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