ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3200 | GCAGAUCAAGACUCUGAAC--- CGUCUAGUUCUGAGACUUG--- |
70 | 34 | 36 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3201 | CAGAUCAAGACUCUGAAC---A GUCUAGUUCUGAGACUUG---U |
65 | 24 | 41 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3202 | AGAUCAAGACUCUGAAC---AA UCUAGUUCUGAGACUUG---UU |
70 | 52 | 18 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3203 | GAUCAAGACUCUGAAC---AAG CUAGUUCUGAGACUUG---UUC |
54 | 0 | 54 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3204 | AUCAAGACUCUGAAC---AAGU UAGUUCUGAGACUUG---UUCA |
70 | 45 | 25 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3205 | UCAAGACUCUGAAC---AAGUU AGUUCUGAGACUUG---UUCAA |
73 | 35 | 38 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3206 | CAAGACUCUGAAC---AAGUUC GUUCUGAGACUUG---UUCAAG |
18 | 60 | -42 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3207 | AAGACUCUGAAC---AAGUUCG UUCUGAGACUUG---UUCAAGC |
42 | 73 | -31 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3208 | AGACUCUGAAC---AAGUUCGC UCUGAGACUUG---UUCAAGCG |
13 | 57 | -44 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3209 | GACUCUGAAC---AAGUUCGCC CUGAGACUUG---UUCAAGCGG |
35 | 58 | -23 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3210 | ACUCUGAAC---AAGUUCGCCU UGAGACUUG---UUCAAGCGGA |
34 | 68 | -34 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3211 | CUCUGAAC---AAGUUCGCCUC GAGACUUG---UUCAAGCGGAG |
9 | 55 | -46 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3212 | UCUGAAC---AAGUUCGCCUCC AGACUUG---UUCAAGCGGAGG |
48 | 44 | 4 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3213 | CUGAAC---AAGUUCGCCUCCU GACUUG---UUCAAGCGGAGGA |
28 | 0 | 28 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3214 | UGAAC---AAGUUCGCCUCCUU ACUUG---UUCAAGCGGAGGAA |
34 | 40 | -6 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3215 | GAAC---AAGUUCGCCUCCUUC CUUG---UUCAAGCGGAGGAAG |
0 | 0 | 0 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3216 | AAC---AAGUUCGCCUCCUUCA UUG---UUCAAGCGGAGGAAGU |
0 | 0 | 0 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3217 | AC---AAGUUCGCCUCCUUCAU UG---UUCAAGCGGAGGAAGUA |
8 | 13 | -5 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3218 | C---AAGUUCGCCUCCUUCAUU G---UUCAAGCGGAGGAAGUAA |
0 | 5 | -5 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3219 | GCAGAUCAAGACUCUGAAC--- CGUCUAGUUCUGAGACUUG--- |
70 | 34 | 36 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3220 | CAGAUCAAGACUCUGAAC---A GUCUAGUUCUGAGACUUG---U |
65 | 24 | 41 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3221 | AGAUCAAGACUCUGAAC---AA UCUAGUUCUGAGACUUG---UU |
70 | 52 | 18 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3222 | GAUCAAGACUCUGAAC---AAG CUAGUUCUGAGACUUG---UUC |
54 | 0 | 54 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3223 | AUCAAGACUCUGAAC---AAGU UAGUUCUGAGACUUG---UUCA |
70 | 45 | 25 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3224 | UCAAGACUCUGAAC---AAGUU AGUUCUGAGACUUG---UUCAA |
73 | 35 | 38 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3225 | CAAGACUCUGAAC---AAGUUC GUUCUGAGACUUG---UUCAAG |
18 | 60 | -42 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3226 | AAGACUCUGAAC---AAGUUCG UUCUGAGACUUG---UUCAAGC |
42 | 73 | -31 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3227 | AGACUCUGAAC---AAGUUCGC UCUGAGACUUG---UUCAAGCG |
13 | 57 | -44 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3228 | GACUCUGAAC---AAGUUCGCC CUGAGACUUG---UUCAAGCGG |
35 | 58 | -23 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3229 | ACUCUGAAC---AAGUUCGCCU UGAGACUUG---UUCAAGCGGA |
34 | 68 | -34 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3230 | CUCUGAAC---AAGUUCGCCUC GAGACUUG---UUCAAGCGGAG |
9 | 55 | -46 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3231 | UCUGAAC---AAGUUCGCCUCC AGACUUG---UUCAAGCGGAGG |
48 | 44 | 4 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3232 | CUGAAC---AAGUUCGCCUCCU GACUUG---UUCAAGCGGAGGA |
28 | 0 | 28 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3233 | UGAAC---AAGUUCGCCUCCUU ACUUG---UUCAAGCGGAGGAA |
34 | 40 | -6 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3234 | GAAC---AAGUUCGCCUCCUUC CUUG---UUCAAGCGGAGGAAG |
0 | 0 | 0 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3235 | AAC---AAGUUCGCCUCCUUCA UUG---UUCAAGCGGAGGAAGU |
0 | 0 | 0 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3236 | AC---AAGUUCGCCUCCUUCAU UG---UUCAAGCGGAGGAAGUA |
8 | 13 | -5 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3237 | C---AAGUUCGCCUCCUUCAUU G---UUCAAGCGGAGGAAGUAA |
0 | 5 | -5 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3238 | AUCAAGACUCUGAAC---AAGU UAGUUCUGAGACUUG---UUCA |
69 | 44 | 25 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA | ||
aspsirna3239 | UCAAGACUCUGAAC---AAGUU AGUUCUGAGACUUG---UUCAA |
71 | 38 | 33 | KRT75 | Hair shaft blebbing | c.545_547del,p.N159del | NA |