| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0549 | CGGAAAAGGAGUUGGACUU GCCUUUUCCUCAACCUGAA |
87 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 | 
|
|
| aspsirna0550 | UGACGGAAAAGGAGUUGGA ACUGCCUUUUCCUCAACCU |
13 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0551 | GUAUGACGGAAAAGGAGUU CAUACUGCCUUUUCCUCAA |
68 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0552 | UCAGUAUGACGGAAAAGGA AGUCAUACUGCCUUUUCCU |
30 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0553 | UGCUCAGUAUGACGGAAAA ACGAGUCAUACUGCCUUUU |
45 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0554 | GCUGCUCAGUAUGACGGAA CGACGAGUCAUACUGCCUU |
47 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0555 | UUUGCUGCUCAGUAUGAC AAACGACGAGUCAUACUG |
83 | 100 | -17 | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna1012 | CUGAACCCCCUCAAAAGCC GACUUGGGGGAGUUUUCGG |
75 | 64 | 11 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1013 | CCUCAAAAGCCAAAAAAUG GGAGUUUUCGGUUUUUUAC |
78 | 44 | 34 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1014 | CCCCAAAAGCCAAAAAAU GGGGUUUUCGGUUUUUUA |
80 | 40 | 40 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1015 | CUGAACCCCCUCAAAAGCC GACUUGGGGGAGUUUUCGG |
75 | 64 | 11 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1016 | CCUCAAAAGCCAAAAAAUG GGAGUUUUCGGUUUUUUAC |
78 | 44 | 34 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1017 | CCCCAAAAGCCAAAAAAU GGGGUUUUCGGUUUUUUA |
80 | 40 | 40 | COL1A1 | Osteogenesis Imperfecta (OI) | c.*88T>C | rs1061237 |
|
|
| aspsirna1886 | UCUCCUGGUGAAGCUUGUC AGAGGACCACUUCGAACAG |
40 | 22 | 18 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1887 | CUCCUGGUGAAGCUUGUCG GAGGACCACUUCGAACAGC |
40 | 25 | 15 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1888 | UCCUGGUGAAGCUUGUCGU AGGACCACUUCGAACAGCA |
52 | 40 | 12 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1889 | CCUGGUGAAGCUUGUCGUC GGACCACUUCGAACAGCAG |
47 | 18 | 29 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1890 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
57 | 2 | 55 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1891 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 10 | 48 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1892 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
65 | 15 | 50 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1893 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
58 | 1 | 57 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1894 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
60 | 15 | 45 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1895 | UGGUGAAGCUUGUCGUCCC ACCACUUCGAACAGCAGGG |
60 | 11 | 49 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|