Total number of Results for Pachyonychia congenita (PC) are 39
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0876 ACAGAUCAAGACCCUCAAA
UGUCUAGUUCUGGGAGUUU
36 22 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0877 CAGAUCAAGACCCUCAAAA
GUCUAGUUCUGGGAGUUUU
56 42 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0878 AGAUCAAGACCCUCAAAAA
UCUAGUUCUGGGAGUUUUU
39 20 19 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0879 GAUCAAGACCCUCAAAAAC
CUAGUUCUGGGAGUUUUUG
56 42 14 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0880 AUCAAGACCCUCAAAAACA
UAGUUCUGGGAGUUUUUGU
67 39 28 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0881 UCAAGACCCUCAAAAACAA
AGUUCUGGGAGUUUUUGUU
89 10 79 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0882 CAAGACCCUCAAAAACAAG
GUUCUGGGAGUUUUUGUUC
30 2 28 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0883 AAGACCCUCAAAAACAAGU
UUCUGGGAGUUUUUGUUCA
33 0 33 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0884 AGACCCUCAAAAACAAGUU
UCUGGGAGUUUUUGUUCAA
35 10 25 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0885 GACCCUCAAAAACAAGUUU
CUGGGAGUUUUUGUUCAAA
59 0 59 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0886 ACCCUCAAAAACAAGUUUG
UGGGAGUUUUUGUUCAAAC
13 0 13 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0887 CCCUCAAAAACAAGUUUGC
GGGAGUUUUUGUUCAAACG
35 0 35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0888 CCUCAAAAACAAGUUUGCC
GGAGUUUUUGUUCAAACGG
45 9 36 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0889 CUCAAAAACAAGUUUGCCU
GAGUUUUUGUUCAAACGGA
56 25 31 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0890 UCAAAAACAAGUUUGCCUC
AGUUUUUGUUCAAACGGAG
45 10 35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0891 CAAAAACAAGUUUGCCUCC
GUUUUUGUUCAAACGGAGG
23 20 3 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0892 AAAAACAAGUUUGCCUCCU
UUUUUGUUCAAACGGAGGA
53 34 19 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0893 AAAACAAGUUUGCCUCCUU
UUUUGUUCAAACGGAGGAA
47 20 27 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna0894 AAACAAGUUUGCCUCCUUC
UUUGUUCAAACGGAGGAAG
34 9 25 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17914454
aspsirna1795 GACCCUCAAAAACAAGUUU
CUGGGAGUUUUUGUUCAAA
15 55 -40 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1796 AGAUCAAGACCCUCAAAAA
UCUAGUUCUGGGAGUUUUU
50 85 -35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1797 CAGAUCAAGACCCUCAAAA
GUCUAGUUCUGGGAGUUUU
44 70 -26 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1798 ACAGAUCAAGACCCUCAAA
UGUCUAGUUCUGGGAGUUU
40 60 -20 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1799 AAAAACAAGUUUGCCUCCUU
UUUUUGUUCAAACGGAGGAA
10 23 -13 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1800 UCAAGACCCUC---AACAAGUU
AGUUCUGGGAG---UUGUUCAA
75 20 55 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926
aspsirna1801 CAAGACCCUC---AACAAGUUU
GUUCUGGGAG---UUGUUCAAA
30 20 10 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926
aspsirna1802 AAGACCCUC---AACAAGUUUG
UUCUGGGAG---UUGUUCAAAC
25 5 20 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926
aspsirna3112 GCACAAGUGACUAGUCCUA
CGUGUUCACUGAUCAGGAU
65 30 35 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3113 CUAGUCCUAUGAUGUACAA
GAUCAGGAUACUACAUGUU
75 30 45 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3114 UCUUCUCUCUCUCUCUAUA
AGAAGAGAGAGAGAGAUAU
78 30 48 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3115 UCUGAGGCUGAGCAUUAUA
AGACUCCGACUCGUAAUAU
79 30 49 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3116 GCACAAGUGACUAGUCCUA
CGUGUUCACUGAUCAGGAU
65 30 35 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3117 CUAGUCCUAUGAUGUACAA
GAUCAGGAUACUACAUGUU
75 30 45 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3118 UCUUCUCUCUCUCUCUAUA
AGAAGAGAGAGAGAGAUAU
78 30 48 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3119 UCUGAGGCUGAGCAUUAUA
AGACUCCGACUCGUAAUAU
79 30 49 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3120 GCACAAGUGACUAGUCCUA
CGUGUUCACUGAUCAGGAU
65 30 35 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3121 GAUCAAGACCCUCAAAAAC
CUAGUUCUGGGAGUUUUUG
56 42 14 KRT6A Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
19935778
aspsirna3122 CCCUCAAAAACAAGUUUGC
GGGAGUUUUUGUUCAAACG
35 0 35 KRT6A Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
19935778
aspsirna3123 CCCUCAAAAACAAGUUUGC
GGGAGUUUUUGUUCAAACG
55 10 45 KRT6A Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
19935778