| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0876 | ACAGAUCAAGACCCUCAAA UGUCUAGUUCUGGGAGUUU |
36 | 22 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | 
|
|
| aspsirna0877 | CAGAUCAAGACCCUCAAAA GUCUAGUUCUGGGAGUUUU |
56 | 42 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0878 | AGAUCAAGACCCUCAAAAA UCUAGUUCUGGGAGUUUUU |
39 | 20 | 19 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0879 | GAUCAAGACCCUCAAAAAC CUAGUUCUGGGAGUUUUUG |
56 | 42 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0880 | AUCAAGACCCUCAAAAACA UAGUUCUGGGAGUUUUUGU |
67 | 39 | 28 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0881 | UCAAGACCCUCAAAAACAA AGUUCUGGGAGUUUUUGUU |
89 | 10 | 79 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0882 | CAAGACCCUCAAAAACAAG GUUCUGGGAGUUUUUGUUC |
30 | 2 | 28 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0883 | AAGACCCUCAAAAACAAGU UUCUGGGAGUUUUUGUUCA |
33 | 0 | 33 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0884 | AGACCCUCAAAAACAAGUU UCUGGGAGUUUUUGUUCAA |
35 | 10 | 25 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0885 | GACCCUCAAAAACAAGUUU CUGGGAGUUUUUGUUCAAA |
59 | 0 | 59 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0886 | ACCCUCAAAAACAAGUUUG UGGGAGUUUUUGUUCAAAC |
13 | 0 | 13 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0887 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
35 | 0 | 35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0888 | CCUCAAAAACAAGUUUGCC GGAGUUUUUGUUCAAACGG |
45 | 9 | 36 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0889 | CUCAAAAACAAGUUUGCCU GAGUUUUUGUUCAAACGGA |
56 | 25 | 31 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0890 | UCAAAAACAAGUUUGCCUC AGUUUUUGUUCAAACGGAG |
45 | 10 | 35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0891 | CAAAAACAAGUUUGCCUCC GUUUUUGUUCAAACGGAGG |
23 | 20 | 3 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0892 | AAAAACAAGUUUGCCUCCU UUUUUGUUCAAACGGAGGA |
53 | 34 | 19 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0893 | AAAACAAGUUUGCCUCCUU UUUUGUUCAAACGGAGGAA |
47 | 20 | 27 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna0894 | AAACAAGUUUGCCUCCUUC UUUGUUCAAACGGAGGAAG |
34 | 9 | 25 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1795 | GACCCUCAAAAACAAGUUU CUGGGAGUUUUUGUUCAAA |
15 | 55 | -40 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1796 | AGAUCAAGACCCUCAAAAA UCUAGUUCUGGGAGUUUUU |
50 | 85 | -35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1797 | CAGAUCAAGACCCUCAAAA GUCUAGUUCUGGGAGUUUU |
44 | 70 | -26 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1798 | ACAGAUCAAGACCCUCAAA UGUCUAGUUCUGGGAGUUU |
40 | 60 | -20 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1799 | AAAAACAAGUUUGCCUCCUU UUUUUGUUCAAACGGAGGAA |
10 | 23 | -13 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna1800 | UCAAGACCCUC---AACAAGUU AGUUCUGGGAG---UUGUUCAA |
75 | 20 | 55 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 |
|
|
| aspsirna1801 | CAAGACCCUC---AACAAGUUU GUUCUGGGAG---UUGUUCAAA |
30 | 20 | 10 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 |
|
|
| aspsirna1802 | AAGACCCUC---AACAAGUUUG UUCUGGGAG---UUGUUCAAAC |
25 | 5 | 20 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 |
|
|
| aspsirna3112 | GCACAAGUGACUAGUCCUA CGUGUUCACUGAUCAGGAU |
65 | 30 | 35 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3113 | CUAGUCCUAUGAUGUACAA GAUCAGGAUACUACAUGUU |
75 | 30 | 45 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3114 | UCUUCUCUCUCUCUCUAUA AGAAGAGAGAGAGAGAUAU |
78 | 30 | 48 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3115 | UCUGAGGCUGAGCAUUAUA AGACUCCGACUCGUAAUAU |
79 | 30 | 49 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3116 | GCACAAGUGACUAGUCCUA CGUGUUCACUGAUCAGGAU |
65 | 30 | 35 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3117 | CUAGUCCUAUGAUGUACAA GAUCAGGAUACUACAUGUU |
75 | 30 | 45 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3118 | UCUUCUCUCUCUCUCUAUA AGAAGAGAGAGAGAGAUAU |
78 | 30 | 48 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3119 | UCUGAGGCUGAGCAUUAUA AGACUCCGACUCGUAAUAU |
79 | 30 | 49 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3120 | GCACAAGUGACUAGUCCUA CGUGUUCACUGAUCAGGAU |
65 | 30 | 35 | KRT6A | Pachyonychia congenita (PC) | NA | NA |
|
|
| aspsirna3121 | GAUCAAGACCCUCAAAAAC CUAGUUCUGGGAGUUUUUG |
56 | 42 | 14 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3122 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
35 | 0 | 35 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3123 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
55 | 10 | 45 | KRT6A | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|