Total number of Results for PSEN1 are 23
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0428 GUGGUUGGUAAAGCCUCAG
CACCAACCAUUUCGGAGUC		 63 93 -30 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0429 UGUGGUUGGUAAAGCCUCA
ACACCAACCAUUUCGGAGU		 53 8 45 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0430 UUGUGGUUGGUAAAGCCUC
AACACCAACCAUUUCGGAG		 54 28 26 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0431 GUUGUGGUUGGUAAAGCCU
CAACACCAACCAUUUCGGA		 72 28 44 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0432 UGUUGUGGUUGGUAAAGCC
ACAACACCAACCAUUUCGG		 38 14 24 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0433 GUGUUGUGGUUGGUAAAGC
CACAACACCAACCAUUUCG		 90 15 75 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0434 AGUGUUGUGGUUGGUAAAG
UCACAACACCAACCAUUUC		 73 40 33 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0435 CAGUGUUGUGGUUGGUAAA
GUCACAACACCAACCAUUU		 69 29 40 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0436 ACAGUGUUGUGGUUGGUAA
UGUCACAACACCAACCAUU		 63 17 46 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0437 UACAGUGUUGUGGUUGGUA
AUGUCACAACACCAACCAU		 65 7 58 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0438 CUACAGUGUUGUGGUUGGU
GAUGUCACAACACCAACCA		 0 0 0 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0439 UCUACAGUGUUGUGGUUGG
AGAUGUCACAACACCAACC		 0 0 0 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0440 UUCUACAGUGUUGUGGUUG
AAGAUGUCACAACACCAAC		 37 0 37 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0441 UUUCUACAGUGUUGUGGUU
AAAGAUGUCACAACACCAA		 15 0 15 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0442 UUUUCUACAGUGUUGUGGU
AAAAGAUGUCACAACACCA		 83 0 83 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0443 AUUUUCUACAGUGUUGUGG
UAAAAGAUGUCACAACACC		 6 0 6 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0444 CAUUUUCUACAGUGUUGUG
GUAAAAGAUGUCACAACAC		 82 0 82 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0445 UCAUUUUCUACAGUGUUGU
AGUAAAAGAUGUCACAACA		 80 22 58 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0446 UUCAUUUUCUACAGUGUUG
AAGUAAAAGAUGUCACAAC		 70 0 70 PSEN1 Alzheimers disease c.811C>G, p.Leu271Val rs63750886
21559198
aspsirna0872 GUCCCGGCAGGUGGUGGAGC
CAGGGCCGUCCACCACCUCG		 60 15 45 PSEN1 Alzheimers disease c.458C>G, p.Leu153Val 63751441
18776243
aspsirna0873 GACCCGGCAGGUGGUGGAGCA
CUGGGCCGUCCACCACCUCGU		 70 20 50 PSEN1 Alzheimers disease c.458C>G, p.Leu153Val 63751441
18776243
aspsirna0874 GUCCCGGCAGGUGGUGGAGC
CAGGGCCGUCCACCACCUCG		 70 10 60 PSEN1 Alzheimers disease c.458C>G, p.Leu153Val 63751441
18776243
aspsirna0875 GACCCGGCAGGUGGUGGAGCA
CUGGGCCGUCCACCACCUCGU		 80 20 60 PSEN1 Alzheimers disease c.458C>G, p.Leu153Val 63751441
18776243