Total number of Results for TOR1A are 15
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0556 CAGAGUGGCU---GAGAUGAC
GUCUCACCGA---CUCUACUG
80 45 35 TOR1A DYT1 dystonia c.907_909delGAG,p.Glu303del rs72415998
12783425
aspsirna0557 CU---GAGAUGACAUUUUUCCCC
GA---CUCUACUGUAAAAAGGGG
4 15 -11 TOR1A DYT1 dystonia c.907_909delGAG,p.Glu303del rs72415998
12783425
aspsirna0558 GAGUGGCU---GAGAUGACAUUUUUC
CUCACCGA---CUCUACUGUAAAAAG
0 27 -27 TOR1A DYT1 dystonia c.907_909delGAG,p.Glu303del rs72415998
12783425
aspsirna0895 AGCAGAGUGGCUGAG---AUGA
UCGUCUCACCGACUC---UACU
46 5 41 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
18258738
aspsirna0896 GCAGAGUGGCUGAG---AUGAC
CGUCUCACCGACUC---UACUG
67 52 15 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
18258738
aspsirna0897 AAGCAGAGUGGCUGAGGAG
UUCGUCUCACCGACUCCUC
74 70 4 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
18258738
aspsirna0898 AGCAGAGUGGCUGAGGAGA
UCGUCUCACCGACUCCUCU
56 34 22 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
18258738
aspsirna0923 GAGUGGCUGAG---AUGACAUU
CUCACCGACUC---UACUGUAA
92 58 34 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
16280588
aspsirna0924 GUGGCUGAG---AUGACAUUUU
CACCGACUC---UACUGUAAAA
85 19 66 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
16280588
aspsirna0925 GUGGCUGAG---AUGACAUUUU
CACCGACUC---UACUGUAAAA
90 12 78 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
16280588
aspsirna0926 GUGGCUGAG---AUGACAUUUU
CACCGACUC---UACUGUAAAA
NA NA NA TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
16280588
aspsirna0927 CAGAGUGGCUGAG---AUGACA
GUCUCACCGACUC---UACUGU
95 15 80 TOR1A Early onset torsion dystonia (DYT1) c.907_909delGAG,p.Glu303del rs72415998
16280588
aspsirna3555 GUGGCCAGAUGGAAGUAAAAUC
CACCGGUCUACCUUCAUUUUAG
70 68 2 TOR1A Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) NA NA
US20080176812A1
aspsirna3556 GUGGCCACAUGGAAGUAAAAUC
CACCGGUGUACCUUCAUUUUAG
55 0 55 TOR1A Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) NA NA
US20080176812A1
aspsirna3557 GUGGCCAGAUGCAAGUAAAAUC
CACCGGUCUACGUUCAUUUUAG
59 10 49 TOR1A Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17) NA NA
US20080176812A1