ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0705 | AGGCAUGUUGGAGACUUGC UCCGUACAACCUCUGAACG |
88 | 78 | 10 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0706 | GGCAUGUUGGAGACUUGCG CCGUACAACCUCUGAACGC |
88 | 55 | 33 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0707 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
92 | 25 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0708 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 40 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0709 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
95 | 40 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0710 | UGUUGGAGACUUGCGCAAU ACAACCUCUGAACGCGUUA |
90 | 35 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0711 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
94 | 60 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0712 | UUGGAGACUUGCGCAAUGU AACCUCUGAACGCGUUACA |
81 | 32 | 49 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0713 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
84 | 46 | 38 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0714 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 32 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0715 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
76 | 25 | 51 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0716 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
85 | 32 | 53 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0717 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
62 | 28 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0718 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
72 | 55 | 17 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0719 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
80 | 75 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0720 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
77 | 32 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0721 | UGCGCAAUGUGACUGCUGA ACGCGUUACACUGACGACU |
84 | 80 | 4 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0722 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
70 | 68 | 2 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0723 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
83 | 82 | 1 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0724 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
88 | 85 | 3 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0725 | AGGCAUGUUGGAGACUUGC UCCGUACAACCUCUGAACG |
88 | 78 | 10 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0726 | GGCAUGUUGGAGACUUGCG CCGUACAACCUCUGAACGC |
88 | 55 | 33 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0727 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
92 | 25 | 67 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0728 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 40 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0729 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
95 | 40 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0730 | UGUUGGAGACUUGCGCAAU ACAACCUCUGAACGCGUUA |
90 | 35 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0731 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
94 | 60 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0732 | UUGGAGACUUGCGCAAUGU AACCUCUGAACGCGUUACA |
81 | 32 | 49 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0733 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
84 | 46 | 38 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0734 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 32 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0735 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
76 | 25 | 51 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0736 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
85 | 32 | 53 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0737 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
62 | 28 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0738 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
72 | 55 | 17 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0739 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
80 | 75 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0740 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
77 | 32 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0741 | UGCGCAAUGUGACUGCUGA ACGCGUUACACUGACGACU |
84 | 80 | 4 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0742 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
70 | 68 | 2 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0743 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
83 | 82 | 1 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0744 | AGGCAUGUUGGAGACUUGC UCCGUACAACCUCUGAACG |
88 | 88 | 0 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0745 | GGCAUGUUGGAGACUUGCG CCGUACAACCUCUGAACGC |
88 | 74 | 14 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0746 | GCAUGUUGGAGACUUGCGC CGUACAACCUCUGAACGCG |
92 | 38 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0747 | CAUGUUGGAGACUUGCGCA GUACAACCUCUGAACGCGU |
94 | 90 | 4 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0748 | AUGUUGGAGACUUGCGCAA UACAACCUCUGAACGCGUU |
95 | 60 | 35 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0749 | UGUUGGAGACUUGCGCAAU ACAACCUCUGAACGCGUUA |
90 | 62 | 28 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0750 | GUUGGAGACUUGCGCAAUG CAACCUCUGAACGCGUUAC |
94 | 92 | 2 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0751 | UUGGAGACUUGCGCAAUGU AACCUCUGAACGCGUUACA |
81 | 55 | 26 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0752 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
84 | 65 | 19 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0753 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 58 | 32 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0754 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
76 | 42 | 34 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0755 | AGACUUGCGCAAUGUGACU UCUGAACGCGUUACACUGA |
85 | 56 | 29 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0756 | GACUUGCGCAAUGUGACUG CUGAACGCGUUACACUGAC |
62 | 54 | 8 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0757 | ACUUGCGCAAUGUGACUGC UGAACGCGUUACACUGACG |
72 | 47 | 25 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0758 | CUUGCGCAAUGUGACUGCU GAACGCGUUACACUGACGA |
80 | 79 | 1 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0759 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
77 | 53 | 24 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0760 | UGCGCAAUGUGACUGCUGA ACGCGUUACACUGACGACU |
84 | 87 | -3 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0761 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
70 | 77 | -7 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0762 | CGCAAUGUGACUGCUGACA GCGUUACACUGACGACUGU |
83 | 87 | -4 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0763 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
49 | 22 | 27 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0764 | AGACUUGAGUAAUGUGACU CCUCUGAACGCGUUACACU |
55 | 32 | 23 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0765 | GACUUGAGCAAUGUGACUG CCUCUGAACGCGUUACACU |
68 | 13 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0766 | ACUUGAGCAGUGUGACUGC UGAACUCGUCACACUGACG |
48 | 32 | 16 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0767 | CUUGAGCAAAGUGACUGCU GAACUCGUUCCACUGACGA |
78 | 23 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0768 | UUGAGCAAUUUGACUGCUG AACUCGUUACACUGACGAC |
98 | 22 | 76 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0769 | GCUUUCAGUUAUAUUGAUG CGAAAGUCAAUAUAACUAC |
89 | 20 | 69 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0770 | GGCUUUCAGCUAUAUUGAU CCGAAAGUCAAUAUAACUA |
35 | 20 | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0771 | UGGCUUUCAGUUAUAUUGA ACCGAAAGUAAAUAUAACU |
87 | 23 | 64 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0772 | UUUGGCUUAAAGUUAUAUU AAACCGAAUUUCAAUAUAA |
80 | 35 | 45 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0773 | GUGGUUGGUGAAGCCUCAG CACCAACCAUUUCGGAGUC |
65 | 11 | 54 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 | ||
aspsirna0774 | UGUGGUUGGCAAAGCCUCA ACACCAACCUUUUCGGAGU |
78 | 45 | 33 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |