ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1018 | UAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUG |
75 | 10 | 65 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1019 | GAGACUUGGGCAAUGUGAC CACUGAACCCGUUACACUG |
85 | 5 | 80 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1020 | GAGACUUGGGCAAUGUGAC CUGUGAACCCGUUACACUG |
80 | 8 | 72 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1021 | GAGACUUGGGCAAUGUGAC CUCAGAACCCGUUACACUG |
75 | 60 | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1022 | GAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUU |
75 | 60 | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1023 | GAGACUUGGGCAAUGUGUC CUCUGAACCCGUUACACUG? |
73 | 55 | 18 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1024 | GAGACUUGGGCAAUGUAAC CUCUGAACCCGUUACACUG? |
75 | 45 | 30 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1025 | GAGACUUGGGCAAUGAGAC CUCUGAACCCGUUACACUG? |
90 | 3 | 87 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1026 | UAGACUUGGGCAAUGUGAC CACUGAACCCGUUACACUG |
85 | 3 | 82 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1027 | UAGACUUGGGCAAUGUGAC CUGUGAACCCGUUACACUG |
85 | 5 | 80 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1028 | UAGACUUGGGCAAUGUGAC CUCAGAACCCGUUACACUG |
60 | 65 | -5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1029 | GAGACUUGGGCAAUGUGUC CUCUGAACCCGUUACACUU |
80 | 58 | 22 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1030 | GAGACUUGGGCAAUGUAAC CUCUGAACCCGUUACACUU |
70 | 55 | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1031 | GAGACUUGGGCAAUGAGAC CUCUGAACCCGUUACACUU |
45 | 45 | 0 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1032 | UAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUU |
72 | 4 | 68 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1033 | GAGACUUGGGCAAUGUGUC CACUGAACCCGUUACACUG |
80 | 3 | 77 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1034 | GAGACUUGGGCAAUGUAAC CUGUGAACCCGUUACACUG |
60 | 2 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |
|
aspsirna1035 | GAGACUUGGGCAAUGAGAC CUCAGAACCCGUUACACUG |
76 | 58 | 18 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | ![]() |