Amino Acid Polarity Hydrophobic Hydrophilic
3(33 %) 6 (67 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(11 %)1(11 %)7 (78 %)

Amino Acid Surface exposureSurface exposedBurried
5(55 %)4 (45 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
2(33 %)4(44 %)3 (23 %)

FlexibilityHighly flexibilityLow flexibility
3(33 %)6 (67 %)


Charge
CRDTTPWWC
P+veN-veO No chargeN
Polarity
CRDTTPWWC
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)