Amino Acid Polarity Hydrophobic Hydrophilic
4(30 %) 9 (70 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
2(15 %)4(30 %)7 (55 %)

Amino Acid Surface exposureSurface exposedBurried
9(69 %)4 (31 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
7(70 %)3(23 %)3 (7 %)

FlexibilityHighly flexibilityLow flexibility
7(53 %)6 (47 %)


Charge
DEMEECASHLPYK
P+veN-veO No chargeN
Polarity
DEMEECASHLPYK
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)