Amino Acid Polarity Hydrophobic Hydrophilic
16(45 %) 19 (55 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
4(11 %)4(11 %)27 (78 %)

Amino Acid Surface exposureSurface exposedBurried
20(57 %)15 (43 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
17(53 %)15(42 %)3 (5 %)

FlexibilityHighly flexibilityLow flexibility
18(51 %)17 (49 %)


Charge
EAIRDTNKAVQSVQSSIGNLIVAIKSVQDYVNKEI
P+veN-veO No chargeN
Polarity
EAIRDTNKAVQSVQSSIGNLIVAIKSVQDYVNKEI
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)