Amino Acid Polarity Hydrophobic Hydrophilic
7(70 %) 3 (30 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
2(20 %)0(0 %)8 (80 %)

Amino Acid Surface exposureSurface exposedBurried
4(40 %)6 (60 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
4(44 %)5(50 %)1 (6 %)

FlexibilityHighly flexibilityLow flexibility
2(20 %)8 (80 %)


Charge
HLVAVIGSYR
P+veN-veO No chargeN
Polarity
HLVAVIGSYR
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)