Amino Acid Polarity Hydrophobic Hydrophilic
4(33 %) 8 (67 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
3(25 %)0(0 %)9 (75 %)

Amino Acid Surface exposureSurface exposedBurried
5(41 %)7 (59 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
4(57 %)3(25 %)5 (18 %)

FlexibilityHighly flexibilityLow flexibility
3(25 %)9 (75 %)


Charge
HRILMRIAQMMT
P+veN-veO No chargeN
Polarity
HRILMRIAQMMT
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)