Amino Acid Polarity Hydrophobic Hydrophilic
3(50 %) 3 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
0(0 %)0(0 %)6 (100 %)

Amino Acid Surface exposureSurface exposedBurried
1(16 %)5 (84 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
1(20 %)4(66 %)1 (14 %)

FlexibilityHighly flexibilityLow flexibility
1(16 %)5 (84 %)


Charge
ILMCFS
P+veN-veO No chargeN
Polarity
ILMCFS
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)