Amino Acid Polarity Hydrophobic Hydrophilic
2(40 %) 3 (60 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
0(0 %)1(20 %)4 (80 %)

Amino Acid Surface exposureSurface exposedBurried
3(60 %)2 (40 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
2(50 %)2(40 %)1 (10 %)

FlexibilityHighly flexibilityLow flexibility
3(60 %)2 (40 %)


Charge
NQVGD
P+veN-veO No chargeN
Polarity
NQVGD
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)