Amino Acid Polarity Hydrophobic Hydrophilic
6(50 %) 6 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
4(33 %)0(0 %)8 (67 %)

Amino Acid Surface exposureSurface exposedBurried
6(50 %)6 (50 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
6(50 %)6(50 %)0 (0 %)

FlexibilityHighly flexibilityLow flexibility
6(50 %)6 (50 %)


Charge
RLNNRARIILRA
P+veN-veO No chargeN
Polarity
RLNNRARIILRA
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)