Amino Acid Polarity Hydrophobic Hydrophilic
5(33 %) 10 (67 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
5(33 %)3(20 %)7 (47 %)

Amino Acid Surface exposureSurface exposedBurried
9(60 %)6 (40 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
6(66 %)3(20 %)6 (14 %)

FlexibilityHighly flexibilityLow flexibility
6(40 %)9 (60 %)


Charge
RRHGDEDMFYMHVRG
P+veN-veO No chargeN
Polarity
RRHGDEDMFYMHVRG
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)