Amino Acid Polarity Hydrophobic Hydrophilic
10(50 %) 10 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
5(25 %)2(10 %)13 (65 %)

Amino Acid Surface exposureSurface exposedBurried
11(55 %)9 (45 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
10(55 %)8(40 %)2 (5 %)

FlexibilityHighly flexibilityLow flexibility
8(40 %)12 (60 %)


Charge
RRLHLEPAFLPYSVKAHECC
P+veN-veO No chargeN
Polarity
RRLHLEPAFLPYSVKAHECC
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)