Amino Acid Polarity Hydrophobic Hydrophilic
5(50 %) 5 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
5(50 %)0(0 %)5 (50 %)

Amino Acid Surface exposureSurface exposedBurried
5(50 %)5 (50 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
5(50 %)5(50 %)0 (0 %)

FlexibilityHighly flexibilityLow flexibility
5(50 %)5 (50 %)


Charge
RWRWRWRWRW
P+veN-veO No chargeN
Polarity
RWRWRWRWRW
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)