Amino Acid Polarity Hydrophobic Hydrophilic
6(50 %) 6 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(8 %)3(25 %)8 (67 %)

Amino Acid Surface exposureSurface exposedBurried
5(41 %)7 (59 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
3(30 %)7(58 %)2 (12 %)

FlexibilityHighly flexibilityLow flexibility
5(41 %)7 (59 %)


Charge
SWLRDIWDWICE
P+veN-veO No chargeN
Polarity
SWLRDIWDWICE
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)