Amino Acid Polarity Hydrophobic Hydrophilic
3(20 %) 12 (80 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
4(26 %)5(33 %)6 (41 %)

Amino Acid Surface exposureSurface exposedBurried
11(73 %)4 (27 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
5(71 %)2(13 %)8 (16 %)

FlexibilityHighly flexibilityLow flexibility
7(46 %)8 (54 %)


Charge
TAFHRDDHETDMELK
P+veN-veO No chargeN
Polarity
TAFHRDDHETDMELK
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)