Amino Acid Polarity Hydrophobic Hydrophilic
5(50 %) 5 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
0(0 %)1(10 %)9 (90 %)

Amino Acid Surface exposureSurface exposedBurried
3(30 %)7 (70 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
1(14 %)6(60 %)3 (26 %)

FlexibilityHighly flexibilityLow flexibility
2(20 %)8 (80 %)


Charge
TDVILMCFSI
P+veN-veO No chargeN
Polarity
TDVILMCFSI
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)