Amino Acid Polarity Hydrophobic Hydrophilic
2(50 %) 2 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(25 %)0(0 %)3 (75 %)

Amino Acid Surface exposureSurface exposedBurried
3(75 %)1 (25 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
2(66 %)1(25 %)1 (9 %)

FlexibilityHighly flexibilityLow flexibility
2(50 %)2 (50 %)


Charge
TLPR
P+veN-veO No chargeN
Polarity
TLPR
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)