Amino Acid Polarity Hydrophobic Hydrophilic
11(55 %) 9 (45 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
3(15 %)1(5 %)16 (80 %)

Amino Acid Surface exposureSurface exposedBurried
8(40 %)12 (60 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
4(25 %)12(60 %)4 (15 %)

FlexibilityHighly flexibilityLow flexibility
4(20 %)16 (80 %)


Charge
TLVDCIRNCIHKILGYTVIA
P+veN-veO No chargeN
Polarity
TLVDCIRNCIHKILGYTVIA
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)