Amino Acid Polarity Hydrophobic Hydrophilic
6(75 %) 2 (25 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(12 %)1(12 %)6 (76 %)

Amino Acid Surface exposureSurface exposedBurried
2(25 %)6 (75 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
3(37 %)5(62 %)0 (1 %)

FlexibilityHighly flexibilityLow flexibility
2(25 %)6 (75 %)


Charge
WEAWVRWI
P+veN-veO No chargeN
Polarity
WEAWVRWI
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)