Amino Acid Polarity Hydrophobic Hydrophilic
3(50 %) 3 (50 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(16 %)2(33 %)3 (51 %)

Amino Acid Surface exposureSurface exposedBurried
3(50 %)3 (50 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
2(40 %)3(50 %)1 (10 %)

FlexibilityHighly flexibilityLow flexibility
3(50 %)3 (50 %)


Charge
WEDWVR
P+veN-veO No chargeN
Polarity
WEDWVR
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)