Amino Acid Polarity Hydrophobic Hydrophilic
5(62 %) 3 (38 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(12 %)2(25 %)5 (63 %)

Amino Acid Surface exposureSurface exposedBurried
3(37 %)5 (63 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
2(28 %)5(62 %)1 (10 %)

FlexibilityHighly flexibilityLow flexibility
3(37 %)5 (63 %)


Charge
WEDWVRWI
P+veN-veO No chargeN
Polarity
WEDWVRWI
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)