Amino Acid Polarity Hydrophobic Hydrophilic
4(80 %) 1 (20 %)

Amino Acid Charge+vely charged-vely chargedNeutral Amino acid
1(20 %)0(0 %)4 (80 %)

Amino Acid Surface exposureSurface exposedBurried
1(20 %)4 (80 %)

DisorderDisorder-promotingOrder-promotingDisorder-order neutral
1(20 %)4(80 %)0 (0 %)

FlexibilityHighly flexibilityLow flexibility
1(20 %)4 (80 %)


Charge
WVRWI
P+veN-veO No chargeN
Polarity
WVRWI
PHydrophobicNhydrophilic



Numerical values of physicochemical properties are based on AAindex database (Kawashima et al. 2008)