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A Database of Antiviral Peptides
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AVP0001 details
AVPid
AVP0001
Sequence
PYVGSGLYRR
Nomenclature
p2-p10
Length
10
Against virus
Avian myeloblastosis virus (AMV)
Virus Family
Retroviridae
Source
RSV gag polyprotein
Uniprot
P03354
Cell line
-
Inhibition/IC
50
50
Unit
μM
Target
Release
Assay
Protease activity assay
Properties
View
Structure
Jmol
Paper
Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins.
Authors
Cameron CE, Grinde B, Jentoft J, Leis J, Weber IT, Copeland TD, Wlodawer A.
Reference
J Biol Chem. 1992
Accession
1331099
