AVP0135 details


AVPidAVP0135
SequenceVFPSDEFDASISQVNEKINQSLAFIRKSDELLHNV
NomenclatureT-112
Length35
Against virusRespiratory syncytial virus (RSV)
Virus FamilyParamyxoviridae
SourceRSV fusion (F) protein
Uniprot P03420
Cell line HEp2
Inhibition/IC50  19
Unit EC50 (μM)
TargetFusion
AssayCytopathic effect
PropertiesView
StructureJmol
PaperPeptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
AuthorsLambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr.
ReferenceProc Natl Acad Sci U S A. 1996
Accession8700906