AVP0142 details


AVPidAVP0142
SequenceDASISQVNEKINQSLAFIRKSDELLHNVNAGKSTT
NomenclatureT-119
Length35
Against virusRespiratory syncytial virus (RSV)
Virus FamilyParamyxoviridae
SourceRSV fusion (F) protein
Uniprot P03420
Cell line HEp2
Inhibition/IC50  8
Unit EC50 (μM)
TargetFusion
AssayCytopathic effect
PropertiesView
StructureJmol
PaperPeptides from conserved regions of paramyxovirus fusion (F) proteins are potent inhibitors of viral fusion.
AuthorsLambert DM, Barney S, Lambert AL, Guthrie K, Medinas R, Davis DE, Bucy T, Erickson J, Merutka G, Petteway SR Jr.
ReferenceProc Natl Acad Sci U S A. 1996
Accession8700906