AVP0421 details


AVPidAVP0421
SequenceAALEAKICHQIEYYFGDF
NomenclatureLAP
Length18
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceHuman lupus autoantigen protein
Uniprot P05455
Cell line Huh7
Inhibition/IC50  12
Unit μg
TargetTranslation
AssayLuciferase assay
PropertiesView
StructureJmol
PaperA peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation.
AuthorsIzumi RE, Das S, Barat B, Raychaudhuri S, Dasgupta A.
ReferenceJ Virol. 2004
Accession15016896