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A Database of Antiviral Peptides
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AVP0421 details
AVPid
AVP0421
Sequence
AALEAKICHQIEYYFGDF
Nomenclature
LAP
Length
18
Against virus
Hepatitis C virus (HCV)
Virus Family
Flaviviridae
Source
Human lupus autoantigen protein
Uniprot
P05455
Cell line
Huh7
Inhibition/IC
50
12
Unit
μg
Target
Translation
Assay
Luciferase assay
Properties
View
Structure
Jmol
Paper
A peptide from autoantigen La blocks poliovirus and hepatitis C virus cap-independent translation and reveals a single tyrosine critical for La RNA binding and translation stimulation.
Authors
Izumi RE, Das S, Barat B, Raychaudhuri S, Dasgupta A.
Reference
J Virol. 2004
Accession
15016896
