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A Database of Antiviral Peptides
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AVP0545 details
AVPid
AVP0545
Sequence
KYKETDLLILFKDDYFAKKNEERK
Nomenclature
LaR2C
Length
24
Against virus
Hepatitis C virus (HCV)
Virus Family
Flaviviridae
Source
Human lupus autoantigen protein
Uniprot
P05455
Cell line
Huh7
Inhibition/IC
50
80-95
Unit
%
Target
Translation
Assay
Filter binding assay
Properties
View
Structure
Jmol
Paper
A peptide derived from RNA recognition motif 2 of human la protein binds to hepatitis C virus internal ribosome entry site, prevents ribosomal assembly, and inhibits internal initiation of translation.
Authors
Pudi R, Ramamurthy SS, Das S.
Reference
J Virol. 2005
Accession
16014945