AVP0582 details


AVPidAVP0582
SequenceRRGRTGRGRRGIYR
Nomenclaturep14
Length14
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceHCV non-structural protein 3
Uniprot P26663
Cell line Huh7
Inhibition/IC50  82.85±7.28
Unit EC50 (μM)
TargetReplication
AssayLuciferase assay
PropertiesView
StructureJmol
PaperNS3 Peptide, a novel potent hepatitis C virus NS3 helicase inhibitor: its mechanism of action and antiviral activity in the replicon system.
AuthorsGozdek A, Zhukov I, Polkowska A, Poznanski J, Stankiewicz-Drogon A, Pawlowicz JM, Zagórski-Ostoja W, Borowski P, Boguszewska-Chachulska AM.
ReferenceAntimicrob Agents Chemother. 2008
Accession18039921