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AVPdb
A Database of Antiviral Peptides
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AVP0623 details | |
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| AVPid | AVP0623 |
| Sequence | RTQRRGRTGRGKPGIYR |
| Nomenclature | HCVA(1484-1500) |
| Length | 17 |
| Against virus | Hepatitis C virus (HCV) |
| Virus Family | Flaviviridae |
| Source | HCV NS3 helicase protein |
| Uniprot | P26664 |
| Cell line | Vero |
| Inhibition/IC50 | 27.1±2.4 |
| Unit |
μM |
| Target | Replication |
| Assay | Helicase assay |
| Properties | View |
| Structure | Jmol |
| Paper | Viral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI). |
| Authors | Borowski P, Heising MV, Miranda IB, Liao CL, Choe J, Baier A. |
| Reference | Biochem Pharmacol. 2008 |
| Accession | 18479669 |