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AVPdb
A Database of Antiviral Peptides
|
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AVP0625 details | |
AVPid | AVP0625 |
Sequence | RRGRTGRGRRGIYR |
Nomenclature | HCV(1487-1500) |
Length | 14 |
Against virus | Hepatitis C virus (HCV) |
Virus Family | Flaviviridae |
Source | HCV NS3 helicase protein |
Uniprot | P26663 |
Cell line | Vero |
Inhibition/IC50 | 0.2±0.01 |
Unit |
μM |
Target | Replication |
Assay | Helicase assay |
Properties | View |
Structure | Jmol |
Paper | Viral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI). |
Authors | Borowski P, Heising MV, Miranda IB, Liao CL, Choe J, Baier A. |
Reference | Biochem Pharmacol. 2008 |
Accession | 18479669 |