AVP0625 details


AVPidAVP0625
SequenceRRGRTGRGRRGIYR
NomenclatureHCV(1487-1500)
Length14
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceHCV NS3 helicase protein
Uniprot P26663
Cell line Vero
Inhibition/IC50  0.2±0.01
Unit μM
TargetReplication
AssayHelicase assay
PropertiesView
StructureJmol
PaperViral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI).
AuthorsBorowski P, Heising MV, Miranda IB, Liao CL, Choe J, Baier A.
ReferenceBiochem Pharmacol. 2008
Accession18479669