AVP0632 details


AVPidAVP0632
SequenceRRGRIGRNPSQVGD
NomenclatureWNV(1959-1972)
Length14
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceWNV NS3 helicase protein
Uniprot P06935
Cell line Vero
Inhibition/IC50  169±6.8
Unit μM
TargetReplication
AssayHelicase assay
PropertiesView
StructureJmol
PaperViral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI).
AuthorsBorowski P, Heising MV, Miranda IB, Liao CL, Choe J, Baier A.
ReferenceBiochem Pharmacol. 2008
Accession18479669