AVP0665 details


AVPidAVP0665
SequenceAAQRRGRVGRNPNQVGD
NomenclatureJEV(1959-1975)
Length17
Against virusWest nile virus (WNV)
Virus FamilyFlaviviridae
SourceJEV NS3 helicase protein
Uniprot P27395
Cell line Vero
Inhibition/IC50  >500
Unit μM
TargetReplication
AssayHelicase assay
PropertiesView
StructureJmol
PaperViral NS3 helicase activity is inhibited by peptides reproducing the Arg-rich conserved motif of the enzyme (motif VI).
AuthorsBorowski P, Heising MV, Miranda IB, Liao CL, Choe J, Baier A.
ReferenceBiochem Pharmacol. 2008
Accession18479669