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A Database of Antiviral Peptides
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AVP0676 details
AVPid
AVP0676
Sequence
CCFLNITNSHVSILQERPPLENRVLTGWGL
Nomenclature
Pcr-400
Length
30
Against virus
Human T-cell leukaemia virus 1 (HTLV 1)
Virus Family
Retroviridae
Source
HTLV-1 envelope glycoprotein (gp21)
Uniprot
P14075
Cell line
HeLa
Inhibition/IC
50
0.28±0.01
Unit
μM
Target
Fusion
Assay
Syncitia assay
Properties
View
Structure
Jmol
Paper
Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope.
Authors
Lamb D, Schuttelkopf AW, van Aalten DM, Brighty DW.
Reference
Retrovirology. 2008
Accession
18680566
