AVP1212 details


AVPidAVP1212
SequenceGELGRLVYLLDGPGYDPI
NomenclatureK5-66-A
Length18
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceSynthetic
Cell line E. coli
Inhibition/IC50  125.4
Unit nM
TargetReplication
AssayFRET assay
PropertiesView
StructureJmol
PaperHigh affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.
AuthorsKugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J.
ReferenceJ Biol Chem. 2012
Accession22965230