AVP1216 details


AVPidAVP1216
SequenceHCIYATTNDALIFSV
NomenclatureK6-10-B
Length15
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceSynthetic
Cell line E. coli
Inhibition/IC50  >>1
Unit nM
TargetReplication
AssayFRET assay
PropertiesView
StructureJmol
PaperHigh affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.
AuthorsKugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J.
ReferenceJ Biol Chem. 2012
Accession22965230