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AVPdb
A Database of Antiviral Peptides
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AVP1218 details | |
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| AVPid | AVP1218 |
| Sequence | GELGRLVYLLDGPGYDPIHCDVVTRGGSHLFNF |
| Nomenclature | CP5-46 |
| Length | 33 |
| Against virus | Hepatitis C virus (HCV) |
| Virus Family | Flaviviridae |
| Source | Synthetic |
| Cell line | E. coli |
| Inhibition/IC50 | 11.3±1.6 |
| Unit |
nM |
| Target | Replication |
| Assay | FRET assay |
| Properties | View |
| Structure | Jmol |
| Paper | High affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants. |
| Authors | Kugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J. |
| Reference | J Biol Chem. 2012 |
| Accession | 22965230 |