AVP1218 details


AVPidAVP1218
SequenceGELGRLVYLLDGPGYDPIHCDVVTRGGSHLFNF
NomenclatureCP5-46
Length33
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceSynthetic
Cell line E. coli
Inhibition/IC50  11.3±1.6
Unit nM
TargetReplication
AssayFRET assay
PropertiesView
StructureJmol
PaperHigh affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.
AuthorsKugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J.
ReferenceJ Biol Chem. 2012
Accession22965230