AVP1221 details


AVPidAVP1221
SequenceGELDELVYLLDGPGYDPIHS
NomenclatureCP5-46A-4D5E
Length20
Against virusHepatitis C virus (HCV)
Virus FamilyFlaviviridae
SourceSynthetic
Cell line E. coli
Inhibition/IC50  22.8
Unit nM
TargetReplication
AssayFRET assay
PropertiesView
StructureJmol
PaperHigh affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants.
AuthorsKugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J.
ReferenceJ Biol Chem. 2012
Accession22965230