AVP2030 details


AVPidAVP2030
SequenceYAGAVVNDL
NomenclatureHSV H2-(7-15)
Length9
Against virusHerpes simplex virus 1 (HSV 1)
Virus FamilyHerpesviridae
SourceHSV ribonucleotide reductase subunit 2
Uniprot P10224
Cell line BHK-21/C13
Inhibition/IC50  52
Unit μM
TargetReplication
AssayRibonucleotide reductase assay
PropertiesView
StructureJmol
PaperMechanism of inhibition of herpes simplex virus (HSV) ribonucleotide reductase by a nonapeptide corresponding to the carboxyl terminus of its subunit 2. Specific binding of a photoaffinity analog, [4'-
AuthorsParadis H, Gaudreau P, Brazeau P, Langelier Y.
ReferenceJ Biol Chem. 1988
Accession2846533