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1425 details
Primary information
CancerPPD ID1425
PMID7768152, 21403917
YEAR1994
SEQUENCEGIGKFLKKAKKFGKAFVKILKK
LENGTH22
NAMEPexigaNAn MSI-78
C-ter ModificationAmidation
N-ter ModificationFree
Linear/CyclicLinear
L/D/MixL
Non-NaturalNone
NATUREAntimicrobial
ACTIVITY75% Cytotoxicity at 0.5 µg/ml
SOURCEHelical peptide with a predominance of one or more amino acids tryptophane-rich
Cancer TypeLymphoma Cancer
ASSAYMTT/MTS assay
Patent IDNone
TissueBlood
CELL LINEU-937
TEST TIME6-h
Secondary information
STRUCTURE
Predicted Structure
DSSP statesCHHHHHHHHTTTHHHHTTTCCC
SMILESNCC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N
External Links
PDB exactPDB partialSP exactSP partialTrEMBL exactTrEMBL partialIEDB exactIEDB partial
2lsaANANANANANANANA